Diabetic nephropathy and non-diabetic kidney disease differential diagnosis prediction model and construction method

Abstract

The invention relates to the field of kidney disease differential diagnosis, in particular to a diabetic nephropathy and non-diabetic kidney disease differential diagnosis prediction model and a construction method. By analyzing clinical and pathological characteristics of patients with type 2 diabetes, factors which have great influence on differential diagnosis results are selected, and a column diagram form is adopted, so the method is simple, clear, popular, easy to understand and convenient for clinical operation. According to the kit, the probability that the patients are subjected to renal needle biopsy pathological diagnosis to be non-diabetic kidney diseases (NDRD) and diabetic nephropathy combined non-diabetic kidney diseases (MIX) can be judged according to initial detection data of the type 2 diabetes patients, and differential diagnosis of the diabetic nephropathy and the non-diabetic kidney diseases in the type 2 diabetes patients is achieved. By means of the probability prediction method, clinical doctors can evaluate the kidney biopsy risk income ratio of the type 2 diabetes kidney injury patient, and meanwhile reference is provided for workers of medical institutions without the kidney biopsy technology.

Description

technical field [0001] The invention relates to the field of differential diagnosis of kidney disease, in particular to a differential diagnosis prediction model and construction method of diabetic nephropathy and non-diabetic kidney disease. Background technique [0002] Diabetes is a growing global health problem. According to the data released by the International Diabetes Federation, there are 425 million people with diabetes (20-79 years old) in the world, and by 2045, this number is expected to rise to 693 million. Diabetic nephropathy (DN) is its main complication and has become the number one cause of chronic kidney disease in China. In the past, the diagnosis of diabetic nephropathy (DN) mainly relied on clinical manifestations, such as the duration of diabetes, diabetic retinopathy, and presence or absence of hematuria. However, with the development of renal biopsy techniques, some patients with clinically diagnosed diabetic nephropathy (DN), especially those wit...

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Problems solved by technology

[0003] At present, there are few predictive models for the differential diagnosis of diabetic nephropathy (DN) and non-diabetic renal disease (NDRD) in patients with type 2 diabetes. The previous models proposed the form of regression equations, which required complex calculations and were not practical.

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