Intelligent dyeing system and method

Abstract

The invention belongs to the technical field of cell observation, and particularly relates to an intelligent dyeing system and method. The system comprises a transmission part which comprises a motion transmission mechanism, a first mechanical arm and a sensor and is used for automatically putting a smear into a dyeing area and taking the smear out of the dyeing area after dyeing, a liquid dripping part which comprises a second mechanical arm, a dyeing liquid dripping pipeline, a cleaning liquid flushing pipeline and a waste liquid collecting pipeline, and is used for dripping dyeing liquid and buffer liquid to the smear and flushing redundant dyeing liquid after dyeing, a mixing part which is used for uniformly mixing the dyeing liquid and the buffer liquid on the smear, a gland part which is used for fixing and sealing the smear, a drying part which is used for drying the smear which is dyed and washed, and a control part which is used for controlling the transmission part, the liquid dripping part, the mixing part, the gland part and the drying part according to preset operation steps. The observation liquid prepared by using the system not only has a better observation effect, but also enables the observation to be more efficient.

Description

Technical field [0001] The present invention belongs to the field of cell smear staining, and more particularly to an intelligent dyeing system and method. Background technique [0002] In order to effectively observe the cells and tissues, it is necessary to treat it before observation with a microscope. Specifically, it is necessary to apply the specimen to the slide to form a single layer uniform coating (referred to as a smear, such as blood, bone marrow, etc.), and the smear is fixed and dried using a special process, and then the dyeing liquid And the buffer is dropped in the smear, the buffer is sufficiently contacted with the coating (the nucleus and cytoplasm are dyed into different colors). After dyeing, the cleaning liquid is flushed with the cleaning liquid to rinse the excess liquid. Ohasia, then dried the flushing smear. The dyeing smear was then placed on the microscope for cell detection. [0003] At present, the above operation is mainly manually operated by the ...

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Problems solved by technology

[0003] At present, the above operations are mainly performed manually by the staff. Different operators have different control over the amount of dyeing solution, the dyeing time, and the degree of dyeing uniformity of the dyeing solution. Observation and analysis under the cell microscope have a great influence on the judgment. Not only is the quality of observation difficult to guarantee, the staff also need to spend a lot of time looking for cells that meet the observation requirements in the smear. The inspection efficiency is very low, which may be due to the inability to identify cells and misidentification Causes misdiagnosis and missed diagnosis. At the same time, because the staining process is more affected by human factors, it is not conducive to the standardization of smear staining results and the stability of staining quality. After staining, automatic machine smears cannot be used for image acquisition and recognition to improve inspection efficiency and timeliness.

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