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Platelet detection system based on error prediction model

A detection system and error prediction technology, applied in the field of biomedicine, can solve the problem of high reagent cost, and achieve the effect of saving reagent cost and improving efficiency

Active Publication Date: 2021-10-01
PEKING UNIV THIRD HOSPITAL
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Problems solved by technology

However, due to the high cost of the reagents used, clinical laboratories only use it in the re-examination process of platelet counts

Method used

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  • Platelet detection system based on error prediction model
  • Platelet detection system based on error prediction model
  • Platelet detection system based on error prediction model

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Embodiment Construction

[0029] The preferred embodiments of the present invention will be described below in conjunction with the accompanying drawings. It should be understood that the preferred embodiments described here are only used to illustrate and explain the present invention, and are not intended to limit the present invention.

[0030] Example:

[0031] 1 object

[0032] A total of 370 samples of PLT-F automatically re-examined by the instrument were collected from randomly selected outpatients who visited Peking University Third Hospital within 10 days in 2020, among which PLT-I9 65 samples per L, PLT-I≥80×10 9 / L samples of 305 cases. Collect the basic information of the sample and relevant blood routine data, including red blood cell count (RBC), mean corpuscular volume (MCV), mean platelet volume (MPV), impedance platelet count (impedance platelet) count, PLT-I), optical platelet count (fluorescence platelet count, PLT-F), large platelet ratio (platelet-larger cell ratio, P-LCR), smal...

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Abstract

The present invention provides a platelet detection system based on an error prediction model. The system comprises a detection part, a control part and a re-detection part, wherein the detection part is used for detecting a portion of a sample based on impedance platelet count, the control part comprises a false positive judgment module, wherein the false positive judgment module can be used for judging by using an error prediction model based on data of the detection part, if the judgment is positive, the other part of the sample is added into the re-detection part for re-detection, and if the judgment is false positive, re-detection is not carried out any more; and the re-detection part is configured to detect the other portion of the sample by using a fluorescence platelet count (PLT-F).

Description

technical field [0001] The present invention relates to the field of biomedicine, in particular to a platelet detection system based on an error prediction model. Background technique [0002] Common platelet detection methods include microscope manual counting method, electrical impedance principle method (impedance platelet count, PLT-I), ordinary optical method (optical platelet count, PLT-O), fluorescence optical method (fluorescence platelet count, PLT-F) , flow cytometry, etc. [0003] The electrical impedance method, also known as the Coulter principle, was proposed by Wallace H. Coulter and others in the mid-1950s. This type of instrument uses sheath flow to wrap platelets and red blood cells through the detection holes in turn. When the particles pass through the detection small When the hole is opened, a current pulse will be formed due to the change of resistance. The larger the amplitude of the pulse, the larger the volume of the particles, and the number of pul...

Claims

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Application Information

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IPC IPC(8): G16H10/40G01N15/10
CPCG16H10/40G01N15/1031G01N2015/1024
Inventor 杨硕李强崔丽艳乔蕊丁杰叶红李晖王小林
Owner PEKING UNIV THIRD HOSPITAL
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