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Anti-adhesion hydrophobic coating formula for pipette tip and preparation process

A hydrophobic coating and anti-adhesion technology, applied in the coating and other directions, can solve the problems of reducing the accuracy of test results, affecting the accuracy of reagents, etc., to meet the needs of mass production, the production process is simple and convenient, and the effect of reducing residues

Inactive Publication Date: 2021-07-23
苏州亚通生物医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing pipette tip is affected by the properties of the material, and a small amount of liquid droplets will adhere to the pipette tip when drawing and discharging the reagent, which will affect the accuracy of reagent pipetting and reduce the accuracy of test results

Method used

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  • Anti-adhesion hydrophobic coating formula for pipette tip and preparation process
  • Anti-adhesion hydrophobic coating formula for pipette tip and preparation process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0023] An anti-adhesion hydrophobic coating formula for a pipette tip, which consists of the following components by weight fraction: 20-35 parts of nano silicon dioxide, 25-40 parts of fluorosilane, and 8-12 parts of polyvinyl alcohol nano-microspheres , 5-20 parts of fixative, 2-4 parts of defoamer, 20-35 parts of solvent.

[0024] Specifically, silicon fluoride is one of tridecafluorooctyltriethoxysilane and perfluorodecyltriethoxysilane, the particle size of polyvinyl alcohol nanospheres is 0.5-0.8 μm, and the curing agent is One of polyamide, phenolic modified amine and epoxy resin, the defoamer is a combination of one or more of alkyl silicone oil, alcohols and oleic acid, the solvent is absolute ethanol, n-propanol, iso A combination of one or more of propanol, acetone, tetrahydrofuran, N, N-dimethylacetamide, N, N-dimethylformamide, toluene and xylene.

[0025] Also provided in this embodiment is a production process for the anti-adhesion hydrophobic coating of the pi...

Embodiment 1

[0036] An anti-adhesion hydrophobic coating formula for a pipette tip, which consists of the following components by weight fraction: 20 parts of nano silicon dioxide, 25 parts of fluorosilane, 8 parts of polyvinyl alcohol nano microspheres, 5 parts of fixative, 2 parts of defoamer, 20 parts of solvent.

[0037] Specifically, the silicon fluoride is tridecafluorooctyltriethoxysilane, the particle size of the polyvinyl alcohol nanospheres is 0.5 μm, the curing agent is polyamide, the defoaming agent is alkyl silicone oil, and the solvent is n-propanol .

Embodiment 2

[0039] An anti-adhesion hydrophobic coating formula for a pipette tip, which consists of the following components by weight fraction: 30 parts of nano silicon dioxide, 35 parts of fluorosilane, 10 parts of polyvinyl alcohol nano microspheres, 10 parts of fixative, 3 parts of defoamer, 30 parts of solvent.

[0040] Specifically, the silicon fluoride is perfluorodecyltriethoxysilane, the particle size of polyvinyl alcohol nanospheres is 0.6 μm, the curing agent is phenolic modified amine, the defoaming agent is alkyl silicone oil, and the solvent is acetone-free.

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Abstract

The invention relates to an anti-adhesion hydrophobic coating formula for a pipette tip and a preparation process, and the hydrophobic coating formula is prepared from the following components in parts by weight: 20-35 parts of nano silicon dioxide, 25-40 parts of fluorosilane, 8-12 parts of polyvinyl alcohol nano microspheres, 5-20 parts of a fixing agent, 2-4 parts of a defoaming agent and 20-35 parts of a solvent. The adopted raw materials are simple and easy to obtain, the preparation technology is simple and convenient, liquid drop residues on the surface of the pipette tip can be effectively reduced, the accuracy of the pipette volume can be improved, the obtained hydrophobic coating is good in transparency and convenient to observe in the liquid taking process, and the requirement for large-batch production can be met by forming in a spraying mode.

Description

technical field [0001] The invention relates to the technical field of pipette tips, in particular to a formula and production process of an anti-adhesion hydrophobic coating for pipette tips. Background technique [0002] Pipette gun is a kind of pipette, which is used to pipette a small amount or a small amount of reagents. It is an essential tool in the fields of biochemical experiments, in vitro diagnostics, etc., and its accuracy often directly affects the test results. The existing pipette tip is affected by the properties of the material, and a small amount of liquid droplets will adhere to the pipette tip when drawing and ejecting the reagent, affecting the accuracy of reagent pipetting and reducing the accuracy of test results. Contents of the invention [0003] In order to solve the above technical problems, the present invention provides a formula and production process of an anti-adhesion hydrophobic coating for pipette tips, which has the advantages of reducin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C09D183/08C09D129/04C09D7/61
CPCC08L2201/10C09D183/08C09D7/61C08L29/04C08K3/36
Inventor 潘健智
Owner 苏州亚通生物医疗科技有限公司
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