Guava hypoglycemic composition and application of composition

A composition, guava technology, applied in the directions of application, drug combination, microorganism, etc., can solve problems such as unsatisfactory hypoglycemic effect

Inactive Publication Date: 2021-07-23
深圳市清生元生物技术股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although guava is often used with other medicines and food or traditional Chinese medicine prescriptions, the actual hypoglycemic effect is not satisfactory

Method used

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  • Guava hypoglycemic composition and application of composition
  • Guava hypoglycemic composition and application of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041]This embodiment provides a composition comprising 20 parts by mass of guava extract, 1 part by mass of the fermentation product of I. coronoidis and 1 part by mass of mulberry extract. In this embodiment, the guava extract is the water extract of guava fruit, the fermentation product of S. coronis is the liquid fermentation product of S. coronis, and the mulberry extract is the water extract of mulberry leaves. Each component The specific preparation method is as follows:

[0042] (1) Get the guava fruit, dry it at 60°C and crush it through a No. 2 sieve (850 μm ± 29 μm, 24 mesh) to obtain the coarse powder of the guava fruit;

[0043] (2) Take 100g of guava fruit coarse powder, prepare 1000mL aqueous solution, heat to 100°C for extraction for 1 hour, filter, and retain the extract;

[0044] (3) The filtered filter residue repeats the extraction process in step (2) twice, combines three parts of extracts, suitably concentrates, and dries at 50° C. to obtain the water ex...

Embodiment 2

[0051] This embodiment provides a composition, which differs from the embodiment 1 in that it includes 20 parts by mass of guava extract, 1 part by mass of the fermentation product of I. coronis and 5 parts by mass of mulberry extract.

Embodiment 3

[0053] This embodiment provides a composition, which differs from the embodiment 1 in that it includes 20 parts by mass of guava extract, 5 parts by mass of the fermentation product of I. coronis and 1 part by mass of mulberry extract.

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Abstract

The invention discloses a guava hypoglycemic composition and application of the composition. In a first aspect of the present application, a composition is provided, the composition includes a guava extract, an eurotium cristatum fermentation product, and a mulberry extract. The composition provided by the embodiment of the invention at least has the following beneficial effects that in the composition provided by the embodiment of the invention, a fermentation product of eurotium cristatum has certain hypoglycemic activity according to experiments, research proves that the fermentation product is safe to a human body, guava also has an application history of reducing blood sugar, meanwhile, folium mori is also a food-sourced raw material, and the composition has a hypoglycemic effect and is safe and non-toxic. According to the present invention, the above three components are used in a matched mode and have a synergistic effect, the inhibition effect on the activity of alpha-glucosidase is remarkably improved, postprandial blood sugar can be effectively reduced, and the blood sugar can be kept stable.

Description

technical field [0001] The application relates to the field of biotechnology, in particular to guava hypoglycemic composition and application thereof. Background technique [0002] Diabetes is one of the most common endocrine diseases. It is a serious threat to human health. It is the third largest chronic non-communicable disease after tumors and cardiovascular diseases. It is also a public health problem that countries all over the world need to face together. Existing therapeutic methods for diabetes include two categories, drug therapy and dietotherapy. Although oral hypoglycemic drugs, subcutaneous insulin injections and other drug treatments have strong hypoglycemic effects and quick onset, they often lack overall coordination, have obvious side effects, and are expensive, which is not conducive to long-term use by diabetic patients. Diet therapy is the basis for the treatment of various types of diabetes. It can lower blood sugar and reduce the burden on islet cells...

Claims

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Application Information

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IPC IPC(8): A61K36/61A61P3/10A23L33/105A23L33/10C12P1/02C12R1/645A61K36/605A61K36/062
CPCA61K36/61A61K36/605A61K36/062A61P3/10A23L33/105A23L33/10C12P1/02A61K2236/19A61K2236/331A23V2002/00A61K2300/00A23V2200/328
Inventor 邹先伟李倩智朋飞
Owner 深圳市清生元生物技术股份有限公司
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