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Antibacterial medical cold compress hydrogel and preparation method thereof

A hydrogel and cold compress technology, applied in the field of antibacterial medical cold compress hydrogel and its preparation, can solve problems such as accelerating wound healing, and achieve the effects of excellent medical value, increasing gel content and relieving pain.

Inactive Publication Date: 2021-07-02
卫纳塞德(北京)医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the past, it was believed that the wound needs to breathe, and maintaining the air permeability of the wound is an important factor for an ideal dressing, but new research proves that an oxygen-free atmospheric environment can promote the proliferation of blood vessels, thereby accelerating wound healing

Method used

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  • Antibacterial medical cold compress hydrogel and preparation method thereof
  • Antibacterial medical cold compress hydrogel and preparation method thereof
  • Antibacterial medical cold compress hydrogel and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The antibacterial medical cold compress hydrogel described in this embodiment, based on the total amount of the hydrogel, includes the following raw material components:

[0032]

[0033] The preparation method of the antibacterial medical cold compress hydrogel described in this embodiment comprises the following steps:

[0034] (1) Get the selected amount of the water-soluble polymer and fully dissolve it in part of deionized water to make a water-soluble polymer solution for subsequent use;

[0035] (2) Dispersing the selected amount of the succinylated modified starch in deionized water to obtain a succinylated modified starch dispersion for subsequent use;

[0036] (3) Mix the obtained water-soluble polymer solution with the succinylated modified starch dispersion, adjust the pH of the system to 9, and keep the temperature at 40° C. for 1 hour;

[0037] (4) Add a selected amount of the antibacterial agent and cross-linking agent to the mixture liquid obtained i...

Embodiment 2

[0039] The antibacterial medical cold compress hydrogel described in this embodiment, based on the total amount of the hydrogel, includes the following raw material components:

[0040]

[0041] The preparation method of the antibacterial medical cold compress hydrogel described in this example is the same as that in Example 1.

Embodiment 3

[0043] The antibacterial medical cold compress hydrogel described in this embodiment, based on the total amount of the hydrogel, includes the following raw material components:

[0044]

[0045] The preparation method of the antibacterial medical cold compress hydrogel described in this example is the same as that in Example 1.

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Abstract

The invention belongs to the technical field of medical biological materials, and particularly relates to an antibacterial medical cold compress hydrogel and a preparation method thereof. According to the antibacterial medical cold compress hydrogel disclosed by the invention, a water-soluble polymer, succinylated modified starch, collagen, a cross-linking agent and deionized water are taken as a raw material system, and the starch is subjected to succinylated modification so as to further improve the gel performance, the water absorption performance and the strength performance of the starch, so that the gel content, the gel strength and other mechanical properties and the water absorption performance of the whole hydrogel system are effectively improved, the cooling effect of the hydrogel can be achieved, and the advantage of cooling is further utilized, so that the hydrogel has the effect of relieving pain; and due to the addition of the antibacterial agent, the antibacterial performance of the whole hydrogel system is effectively improved, and the medical value is better.

Description

technical field [0001] The invention belongs to the technical field of medical biological materials, and in particular relates to an antibacterial medical cold compress hydrogel and a preparation method thereof. Background technique [0002] The rise of hydrogel dressings benefited from a major conceptual breakthrough in wound healing in the 1980s. Previous treatments believed that wounds need to breathe, and maintaining the air permeability of wounds is an important factor for ideal dressings, but new research proves that an oxygen-free atmospheric environment can promote the proliferation of blood vessels, thereby accelerating wound healing. Hydrogel dressings have been widely valued due to their advantages of automatically adjusting the moisture of the wound, absorbing a small amount of exudate, not sticking to the wound, and being easy to remove. [0003] A conventional hydrogel is a polymer material with a three-dimensional cross-linked network structure, and water is ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00A61F7/02C08J3/075C08J3/24C08L39/06C08L3/06C08L89/00C08L1/02C08L29/04
CPCA61L26/008A61L26/0066A61L26/0052A61L26/0061A61F7/02C08J3/075C08J3/246A61L2300/232A61L2300/404A61F2007/0219C08J2339/06C08J2403/06C08J2489/00C08J2401/02C08J2303/06C08J2429/04C08J2389/00
Inventor 王威田霞张俊杰张怡婷朱小龙杨成
Owner 卫纳塞德(北京)医疗科技有限公司
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