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Biological safety bin for small animal living body fluorescence imager and fluorescence imager

A living fluorescence and biosafety technology, which is applied in the fields of restraining animals, using fluorescence emission for analysis, veterinary instruments, etc. Less and easy to operate

Pending Publication Date: 2021-06-22
无锡博医光电技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing biological safety chamber includes two chambers inside and outside. The inner chamber is used to place the living animals, and the outer chamber is used to accommodate the inner chamber and other necessary parts. The structure of the two chambers leads to the overall size of the biological safety chamber. In addition, because the operation of putting live animals into the biosafety chamber is performed in a biosafety cabinet, the experimenter wears thick rubber gloves to operate, and the trachea connection between the inner and outer chambers needs to be manually connected by the experimenter , the operation is cumbersome, and it is easy to cause gas leakage in the biosafety chamber due to inconvenient operation

Method used

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  • Biological safety bin for small animal living body fluorescence imager and fluorescence imager
  • Biological safety bin for small animal living body fluorescence imager and fluorescence imager
  • Biological safety bin for small animal living body fluorescence imager and fluorescence imager

Examples

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Effect test

Embodiment 1

[0038] The present invention provides a biological safety chamber for a small animal live fluorescence imager, including a safety chamber body 1, such as figure 1 , image 3 , Figure 6 , Figure 7 As shown, the safe bin body 1 includes:

[0039] Cartridge 11;

[0040] Canopy cover 12; said canopy box 11 is detachably connected with said canopy cover 12 to clamp together to form a compartment 13; through the detachable connection between the compartment box 11 and the canopy cover 12, so as to open or close the compartment 13, so that For picking and placing live small animals (such as mice);

[0041] High-efficiency filter 20, in order to filter the gas that described chamber 13 discharges; Because small animal living body has pathogenic bacteria, and in experiment process, can be mixed with the hair of small animal living body in the air in chamber 13, in chamber 13 After the air is filtered by the high-efficiency filter 20, the content of particulate impurities and hai...

Embodiment 2

[0062] The present invention provides a fluorescence imager, including an imaging device, and a biosafety chamber for a small animal in vivo fluorescence imager as described above; the detection port of the imaging device is aligned with the transparent window 121 of the safety chamber body 1 . When performing fluorescence imaging analysis, the image acquisition port of the imaging device is positioned above the transparent window 121 , and the small animal on the stage 30 is photographed through the transparent window 121 for fluorescence imaging analysis.

[0063] Compared with the prior art, the present invention improves the biosafety chamber for small animal live fluorescence imagers, which has a compact structure, and the carrier plate is easy to fix the small animal living body, reducing the probability of toxic gas leakage caused by improper operation of the gas pipe, and is safe. The warehouse body is easy to operate, and it is convenient to transfer small animals.

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Abstract

The invention provides a biological safety bin for a small animal living body fluorescence imaging instrument. A safety bin body comprises a bin box, a bin cover, a high-efficiency filter, a negative pressure system and a carrying plate; the bin box and the bin cover are detachably connected so as to jointly clamp to form a bin chamber; the high-efficiency filter is used for filtering gas discharged from the bin; the negative pressure system is used for forming a negative pressure environment in the bin; the carrying plate is arranged in the bin and used for fixing small animal living bodies; the bin cover is provided with a transparent window which is used for being matched with a fluorescence imager to carry out imaging on the small animal living bodies on the carrying plate. The invention also provides the fluorescence imager. The carrying plate is adopted to fix the small animal living bodies, the carrying plate is small in structure and small in occupied bin space, and miniaturization design of the safety bin body is facilitated; the operation of fixing the small animal living bodies by the carrying plate is simple and convenient, and experimenters can easily carry thick gloves to operate; the safety bin body is only provided with a bin box external air pipe which needs to be manually communicated by a laboratory technician, operation is little, and the probability of poisonous gas leakage caused by improper operation during air pipe connection is reduced.

Description

technical field [0001] The invention relates to the technical field of biological safety protection, in particular to a biological safety chamber and a fluorescent imager for small animal live fluorescence imagers. Background technique [0002] In the research work on pathogenic viruses, experiments are usually carried out on living animals with pathogenic bacteria with fluorescence imaging analysis. During this experiment, a biosafety chamber is usually used to safely transfer live animals with pathogenic bacteria. The existing biological safety chamber includes two chambers inside and outside. The inner chamber is used to place the living animals, and the outer chamber is used to accommodate the inner chamber and other necessary parts. The structure of the two chambers leads to the overall size of the biological safety chamber. In addition, because the operation of putting live animals into the biosafety chamber is performed in a biosafety cabinet, the experimenter wears ...

Claims

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Application Information

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IPC IPC(8): A61B5/00A61D3/00
CPCA61B5/0071A61D3/00
Inventor 章强杨任兵
Owner 无锡博医光电技术有限公司
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