A pressure dressing for hemostasis capable of promoting wound healing

A wound and hemostatic tablet technology, applied in the emulsification method and its application in surgical medicine, can solve the problems of reducing the efficacy of Yunnan Baiyao, failing to achieve hemostatic effect, and speeding up wound healing, so as to facilitate wound recovery and improve wound healing. Drug efficacy, effect of promoting wound healing

Active Publication Date: 2021-11-30
南昌华安众辉健康科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the patch is only suitable for the hemostasis of small wounds or to speed up the healing of wounds that have already stopped bleeding
For continuous bleeding, or large wounds, the patch does not have a rapid hemostasis effect
[0004] For continuous bleeding or larger wounds, compression hemostasis is a more effective treatment, but if the above-mentioned patch is directly used as the contact interface, by applying pressure, combined with compression hemostasis to achieve hemostasis and promote wound healing, then The following situations are likely to occur: the drug core that has absorbed wound bleeding and exudate continues to contact the wound, not only cannot discharge the exudate in time, it is not conducive to wound healing, and the drug concentration will also be diluted by blood and exudate, reducing Yunnan Baiyao. efficacy of

Method used

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  • A pressure dressing for hemostasis capable of promoting wound healing
  • A pressure dressing for hemostasis capable of promoting wound healing
  • A pressure dressing for hemostasis capable of promoting wound healing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] The present embodiment provides a kind of emulsification method of Yunnan Baiyao, specifically as follows:

[0051] S1. Take borneol and absolute ethanol, prepare 0.01 g / mL 3 The borneol ethanol solution;

[0052] S2. Take 100 g of Yunnan Baiyao powder and 1400 mL of 50 wt% ethanol, extract Yunnan Baiyao powder four times with ethanol, and use a rotary evaporator to remove part of the ethanol from the obtained extract to obtain an extract with a specific gravity of 1.15 / 25°C.

[0053] S3. Take extract 10 g, Tween 80 0.5 g, water 70 mL, dissolve.

[0054] S4. Melt the beeswax at 70°C, add the solution obtained in S3 to the melted beeswax, emulsify with ultrasound, and quench the obtained emulsion to obtain emulsified material of Yunnan Baiyao.

[0055] The emulsified material is cut and punched, and laser technology is the preferred method of cutting and punching.

[0056] The obtained longitudinal section structure of the Yunnan Baiyao layer along the thickness direc...

Embodiment 2

[0058] This embodiment provides a pressure layer of a hemostatic pressure dressing capable of promoting wound healing.

[0059] The structure of the pressurized layer includes: a timing unit and a pressurized unit 2 .

[0060] like figure 2 As shown, the timing unit is composed of an expansion liquid 1, an expansion body 3, a puncture needle 4, and a pierceable capsule 5 wrapped in a dissolving liquid;

[0061] In this embodiment, the pressurizing unit is a cylindrical structure, surrounding and forming a space that can accommodate the capsule 5 , the expansion body 3 and the puncture needle 4 . The expansion body 3 communicates with the expansion liquid 1 through a small hole, and the aperture of the small hole is designed according to the product requirements, so that the expansion liquid is absorbed by the expansion 3 within the design time, so that the expansion body 3 expands downward. A puncture needle is connected to the end of the expansion body 3, and when the expa...

Embodiment 3

[0065] This embodiment provides a hemostatic pressure dressing capable of promoting wound healing, the preparation method of which is as follows:

[0066] First, the preparation of Yunnan Baiyao layer includes the following steps,

[0067] S1. Take borneol and absolute ethanol, prepare 0.012 g / mL 3 borneol / ethanol solution;

[0068] S2. Take 100 g of Yunnan Baiyao powder and 1400 mL of 50 wt% ethanol, extract Yunnan Baiyao powder four times with ethanol, and use a rotary evaporator to remove part of the ethanol from the obtained extract to obtain an extract with a specific gravity of 1.15 / 25°C.

[0069] S3. Extract 27 g, Tween 80 1.5 g, water 130 ml, dissolve.

[0070] S4. Melt the beeswax at 70°C, add the solution obtained in step S3 to the melted beeswax, emulsify with ultrasound, and quench the obtained emulsion to solidify to obtain the emulsified material of Yunnan Baiyao.

[0071] The solid drug block obtained in step S4 is cut into sheets with a thickness of 0.1-1 ...

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Abstract

In the emulsification method of Yunnan Baiyao provided by the present invention, the effective components of Yunnan Baiyao are extracted, combined with borneol and emulsifier, and beeswax to prepare uniformly dispersed Yunnan Baiyao tablets. Maintain no deformation. The pressure dressing for hemostasis that can promote wound healing prepared by using the Yunnan Baiyao hemostasis tablet can stop bleeding immediately while maintaining the good efficacy of Yunnan Baiyao and promote wound healing. Moreover, the microporous structure on Yunnan Baiyao hemostatic tablets can absorb and transfer wound exudate and blood in time, which is beneficial to wound recovery. In addition, the dressing provided by the present application can be applied to different wounds through changes in shape and size, and has a wide range of applications.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to an emulsification method of traditional Chinese medicine and its application in medical surgery. Background technique [0002] Yunnan Baiyao is a traditional famous medicine that has been clinically proven to stop bleeding and heal wounds, but its traditional dosage form is powder, which has some shortcomings. For example, when the trauma wound is small, Yunnan Baiyao powder cannot be effectively applied to the wound surface; or , When the wound is still bleeding continuously, Yunnan Baiyao powder is easily taken away from the wound by the blood, and cannot effectively exert its medicinal effect. [0003] For this reason, Chinese invention CN1136904C has disclosed a kind of patch and its preparation method that utilizes Yunnan Baiyao to treat skin wound. The patch includes medicament, adhesive tape and drug core. Compared with traditional Yunnan Baiyao pow...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/42A61K36/258A61K36/8945A61K9/20A61P17/02A61P7/04A61L15/44A61F13/02A61F13/00A61B17/12
CPCA61B17/12A61B2017/12004A61F13/00008A61F13/00029A61F13/00063A61F13/00068A61F13/0203A61F2013/00174A61K9/2013A61K9/2072A61K9/2095A61K36/185A61K36/258A61K36/28A61K36/53A61K36/8945A61L15/42A61L15/44A61L2300/418A61L2300/602A61P7/04A61P17/02A61K2300/00
Inventor 陈华
Owner 南昌华安众辉健康科技股份有限公司
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