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Peach gum extract as well as preparation method and application thereof

A technology of extract and peach gum, which is applied in the field of peach gum extract and its preparation, can solve the problems that the safety of surfactants cannot be guaranteed at the same time

Active Publication Date: 2021-06-04
BEIJING ACAD OF TCM BEAUTY SUPPLEMENTS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above methods cannot guarantee the functional performance and safety of use of surfactants at the same time.

Method used

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  • Peach gum extract as well as preparation method and application thereof
  • Peach gum extract as well as preparation method and application thereof
  • Peach gum extract as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0124] Embodiment 1, anti-surfactant stimulates raw material screening

[0125] The present invention screens a variety of Chinese medicine raw materials and compounds that claim to have anti-stimulation and extracts them, and through the red blood cell hemolysis and coagulation test, investigates the antagonistic effect of each Chinese medicine extract on the red blood cell stimulation caused by SDS.

[0126] The present invention also investigated the antagonistic effect of different polysaccharides and three competing products on the red blood cell stimulation caused by SDS.

[0127] Table 1 Sources of raw materials used

[0128]

[0129]

[0130] Market Competitor 1 Ingredients: Butylene Glycol, Water, Centella Asiatica (Centella Asiatica) Extract, Polygonum Cuspidatum Root Extract, Scutellaria Baicalensis Root Extract, Tea (Camellia Sinensis) Leaf Extract, Light Glycyrrhiza Glabra Root Extract, Chamomilla Recutita Flower Extract, Rosemary (Rosmarinus Officinalis) L...

Embodiment 2

[0167] Preparation process:

[0168] According to peach gum: water = 1:20 (m / m), extract with pure water, extract at 70°C for 1.5h; centrifuge at 5000rpm / min for 10min, take the supernatant; use a 50nm microfiltration membrane module for microfiltration and concentration, remove For substances with a molecular weight below 50wDa in the supernatant, retain the effluent to obtain a microfiltrate; add the microfiltrate and 95% ethanol at a ratio of 1: 10 (m / v), stir evenly, and after standing at room temperature for 12 hours, take out the precipitated substance; Freeze-dry at -80°C for 10 hours; pulverize; sterilize at 120°C for 1 hour to obtain peach gum macromolecular polysaccharide extract.

Embodiment 3

[0170] Preparation process:

[0171] According to peach gum: water = 1:10, extract with pure water, extract at 80°C for 0.5h, centrifuge at 4000-8000rpm for 25min, and take the supernatant; use a 50nm microfiltration membrane module to perform microfiltration and concentration, and remove the molecular weight in the supernatant For substances below 50wDa, keep the effluent to obtain the microfiltrate; add the microfiltrate and 95% ethanol at a ratio of 1:5 (m / v), stir evenly, and after standing at room temperature for 10h, take out the precipitated substance and freeze at -50°C Dry for 32 hours, pulverize, and sterilize at 140°C for 0.5 hours to obtain peach gum macromolecular polysaccharide extract.

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Abstract

The invention provides a peach gum extract. The peach gum extract comprises the following components in percentage by mass of 30% or more of peach gum polysaccharide, and the average molecular weight of the peach gum polysaccharide is 100-500 wDa. The invention also provides a preparation method of the peach gum extract. The peach gum extract provided by the invention has a remarkable effect of antagonizing irritation of a surfactant. The invention also provides application of polysaccharide and / or plant extract in preparation of a product for antagonizing irritation of the surfactant.

Description

technical field [0001] The invention relates to a peach gum extract and its preparation method and application. Background technique [0002] Surfactants have multiple functions such as dispersion, decontamination, solubilization and penetration, and are widely used in various detergents and cleaning compositions to impart their cleaning properties, and are an important part of cosmetics. Surfactants can be divided into ionic surfactants and nonionic surfactants according to the characteristics of molecular composition and the dissociation properties of polar groups. [0003] The irritation or sensitization of surfactants to the skin or mucous membranes is mainly reflected in three aspects: (1) Dissolution: the dissolution of surfactants on the skin's own moisturizing ingredients, intercellular lipids, and free amino acids and fats in the stratum corneum. Dissolution degree. Surfactants will affect the degree of dissolution of the skin's own moisturizing ingredients (such ...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/73A61K8/9794A61K8/9728A61Q19/00A61Q19/10A61Q5/02A61Q5/12
CPCA61K8/9789A61K8/73A61K8/9794A61K8/9728A61Q19/00A61Q19/10A61Q5/02A61Q5/12A61K2800/596
Inventor 孟宏刘有停苏牧楠曲召辉刘宇红刘月恒
Owner BEIJING ACAD OF TCM BEAUTY SUPPLEMENTS
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