Use of clean and dry gas for particle removal and assembly therefor

A particle and component technology, applied in the field of sample imaging devices, can solve problems such as slowness and difficulty in counting colonies

Pending Publication Date: 2021-06-01
RAPID MICRO BIOSYSTEMS INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Microbial enumeration is simple, ultra-sensitive, cheap and quantitative, but can also be slow
Colonies can be imaged digitally; however, in some cases, dust and other debris can make colony counting more difficult

Method used

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  • Use of clean and dry gas for particle removal and assembly therefor
  • Use of clean and dry gas for particle removal and assembly therefor
  • Use of clean and dry gas for particle removal and assembly therefor

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Embodiment Construction

[0016] The present invention features particulate removal assemblies and methods for removing dust and other debris from sample containers, such as to improve the detection of microorganisms present in environmental samples, pharmaceutical samples, biological samples, and other samples (such as Bacteria, fungi, or protozoa) colonies are counted. The assembly of the present invention includes components for particulate removal such as filters, dryers, flow controllers and outlets.

[0017] Particle removal components

[0018] Dust and other particulate matter (eg solid particles, water or oil) on the sample container can interfere with accurate detection eg imaging of the sample eg for microbial enumeration. The particulate removal assembly of the present invention helps reduce false positives in colony counts by removing dust and other debris from portions of sample containers, such as the lid or bottom, through which detection, such as imaging, is performed. In particular...

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Abstract

The invention features particle removal assemblies and methods for removing dust and other debris from a sample container, e.g., to improve counting colonies of microorganisms (e.g., bacteria, fungi, or protists) present in environmental, pharmaceutical, biological, and other samples. An assembly of the invention includes components for particle removal, e.g., a filter, a dryer, a flow controller, and an outlet. The invention also provides methods of detecting samples after cleaning a sample container with clean and / or dry gas.

Description

Background technique [0001] In various industries, especially the food, beverage, healthcare, electronics and pharmaceutical industries, it is necessary to quickly analyze samples for the degree of contamination caused by microorganisms such as bacteria, yeast or mold. [0002] A microbial culture technique known as a microbial count or colony count quantifies the number of microbial cells in a sample. Microbial enumeration methods based on in situ microbial replication typically produce a visually detectable "colony" for each microbial cell in the sample. Thus, counting visible colonies allows microbiologists to precisely determine the number of microbial cells in a sample. To perform microbial enumeration, bacterial cells can be dispersed on the surface of nutrient agar in a Petri dish ("agar plate") and cultured under conditions that allow the bacteria to multiply in situ. Microbial enumeration is simple, ultrasensitive, cheap and quantitative, but can also be slow. Colo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N1/22B01D53/00G01N1/00G01N1/02
CPCC12M39/00B01D53/26B01D2258/06G01N1/34G01N15/0612C12M41/36G01N35/00B01D53/268B01D53/263B01D53/261B01D46/0027G01N35/04G01N2035/0437
Inventor R·希金斯K·弗拉顿
Owner RAPID MICRO BIOSYSTEMS INC
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