Traditional Chinese medicine prescription for treating liver cancer and applications

Abstract

The invention discloses a traditional Chinese medicine prescription (liver cancer agreement party GAXD) for treating liver cancer. The prescription consists of 5 parts of paniculate bolbostemma, 3 parts of radix stephaniae tetrandrae, 1 part of rhubarb root and rhizome, 2-3 parts of Sichuan lovage rhizome and 3-5 parts of radix astragali. A preparation method includes the following steps: adding the rhubarb root and rhizome into a cup and a half of water, then adding the paniculate bolbostemma, the radix stephaniae tetrandrae, the Sichuan lovage rhizome and the radix astragali, and performing boiling with low heat for 20-30 min so as to obtain the prescription. Applications of the prescription in preparation of drugs capable of inhibiting the growth of liver cancer tumor are further disclosed. Laboratory findings show that the prescription can inhibit the in-vitro growth and virus replication of HBV + hepatic tumor cells through an STAT3 signal passage, and GAXD can have adjusting effects on the proportion and activity of NK cells in in-vivo experiments.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine treatment, and relates to a traditional Chinese medicine prescription for treating liver cancer (liver cancer agreement prescription GAXD) and its application. Background technique [0002] The Registry Survey of Primary Liver Cancer in China (CLCS) shows that the hepatocellular carcinoma in my country is significantly different from that in European and American countries in many aspects, and has a high degree of heterogeneity, most of which are closely related to hepatitis B virus infection, and often It has reached the middle and late stage, and the chance of surgery has been lost. The treatment is difficult, the prognosis is poor, and the survival period is short. ) and abnormal immune function. [0003] The study of malignant tumors was first initiated by the theoretical system of western medicine. Most of the research is based on the theory of cells, and in the direction ...

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Problems solved by technology

[0002] The Registry Survey of Primary Liver Cancer in China (CLCS) shows that the hepatocellular carcinoma in my country is significantly different from that in European and American countries in many aspects, and has a high degree of heterogeneity, most of which are closely related to hepatitis B virus infection, and often It has reached the middle and late stage, and the chance of surgery has been lost. The treatment is difficult, the prognosis is poor, and the survival period is short. ) and conditions such as immune dysfunction

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