Buckle structure and method for simulating tail suspension of weightless rats

Abstract

The invention discloses a buckle structure and a method for simulating weightless rat tail suspension. The buckle structure includes: a rope body, a first gauze, a second gauze, a first adhesive tape and a second adhesive tape, the first gauze and the second gauze The two gauzes are respectively wrapped around the tail of the mouse and are all cylindrical after being wound. The cylindrical height of the first gauze is less than the cylindrical height of the second gauze, and the second gauze is covered outside the first gauze. The adhesive tape and the second adhesive tape are respectively fixed on the tail of the mouse, the first adhesive tape and the second adhesive tape are respectively located outside the second gauze on the front and rear sides of the first gauze, the rope body is parallel to the tail of the mouse, and the rope body is located outside the second gauze And it is fixed on the tail by the first adhesive tape and the second adhesive tape. The buckle structure of the present invention only needs to apply less tail-tying force and less air-permeable materials, which reduces the stress on rats and greatly improves the success rate of modeling.

Description

technical field [0001] The invention belongs to the technical field of animal simulated weightlessness, and in particular relates to a buckle structure and a tail suspension method for simulating weightlessness rats. Background technique [0002] The current development of manned spaceflight technology is getting faster and faster. When astronauts enter space, the gravity they experience is only one millionth of the gravity on the ground, and the human body is in a state of weightlessness. Long-term exposure to a microgravity environment will have varying degrees of impact on the astronauts' musculoskeletal system, cardiovascular system, immune system, and endocrine system, specifically manifested in muscle atrophy, osteoporosis, physical imbalance, decreased immunity, or cognitive decline other body damage or dysfunction. [0003] In response to these effects, researchers have carried out a number of experiments, but at present there are many limitations in the actual spac...

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Problems solved by technology

[0003] In response to these effects, researchers have carried out a number of experiments, but at present there are many limitations in the actual space experiment operation, and ground-based experiments such as the human body -6° head-down bed test, parabolic flight, neutral buoyancy tank training, etc. are also recruiting subjects. Difficulty, short weightlessness time, and many other influencing factors, cannot restore the space weightlessness environment well

Therefore, at present, rodents such as rats are often used to simulate weightlessness models. The most commonly used modeling method is 30° tail suspension. The stimulation and tightening of the tail caused serious damage to the skin of the tail, which in turn led to infection and necrosis, which affected further experiments and was not conducive to the experimental research on the effects of simulating the effects of medium and long-term spaceflight.

For rats using the traditional tail-tying method, the tail-tying time is mostly 7-14 days. If the time is too long, the tail of the rat will be red, swollen and festered, and the rats will be stressed. This traditional tail-tying method is not suitable for simulating long-term space flight

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