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Composition for enhancing immunity and application

A technology for enhancing immunity and composition, applied to the composition and application field for enhancing immunity, can solve problems such as lack of intervention means, and achieve the effects of enhanced monocyte-macrophage function and enhanced humoral immune function

Inactive Publication Date: 2021-02-23
INST OF ENVIRONMENTAL MEDICINE & OCCUPATIONAL MEDICINE ACAD OF MILITARY MEDICINE ACAD OF MILITARY SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although great progress has been made in the research on the harm of chronic psychological stress, there is still a lack of effective intervention methods for the harm

Method used

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  • Composition for enhancing immunity and application
  • Composition for enhancing immunity and application
  • Composition for enhancing immunity and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A composition for enhancing immunity, comprising 0.25 parts of zinc, 0.025 parts of vitamin A, 3.75 parts of vitamin C, 0.5 parts of vitamin E, 7.5 parts of taurine and 1.5 parts of grape seed extract.

[0038] Preparation of the solution containing the composition of the present invention: respectively accurately weigh zinc gluconate, vitamin A acetate, vitamin C, D-alpha-tocopheryl acetate, taurine, and grape seed extract in the composition of Example 1 , the above raw materials were mixed step by step from small to large by weight and fully mixed to prepare the composition of the embodiment of the present invention.

[0039] The composition of the example was dissolved in distilled water to make a working solution for gastric administration, with a concentration of 4.1 mg / ml, for effect evaluation.

[0040] Evaluation:

[0041] Select adult male C57BL / 6J mice, body weight 22-25g, be divided into 3 groups randomly according to body weight, be respectively control gro...

Embodiment 2

[0057] A composition for enhancing immunity, comprising 0.125 parts of zinc, 0.0125 parts of vitamin A, 1.875 parts of vitamin C, 0.25 parts of vitamin E, 3.75 parts of taurine and 0.75 parts of grape seed extract.

[0058] The preparation of the composition solution of this embodiment is the same as the preparation of the composition solution of Example 1.

[0059] Experiments have shown that the results of the above-mentioned experiments carried out in Examples 2 and 3 are similar to those of Example 1.

Embodiment 3

[0061] A composition for enhancing immunity, comprising 0.5 parts of zinc, 0.05 parts of vitamin A, 7.5 parts of vitamin C, 1 part of vitamin E, 15 parts of taurine and 3 parts of grape seed extract.

[0062] The preparation of the composition solution of this embodiment is the same as the preparation of the composition solution of Example 1.

[0063] Experiments have shown that the results of the above-mentioned experiments carried out in Examples 2 and 3 are similar to those of Example 1.

[0064] The above-mentioned experimental results show that the composition of the present invention significantly increases the number of white blood cells and thymus index, and improves the level of immunoglobulin, reduces the expression of glucocorticoid and C-reactive protein, and enhances the cellular immune function, humoral immune function, and monotherapy of mice in the model group. Nuclear-macrophage immune function, its mechanism of action may be related to neuro-endocrine-immune ...

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PUM

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Abstract

The invention relates to a functional composition, in particular to a composition for enhancing immunity and application. The composition comprises the following components in parts by weight: 0.125 to 0.5 part of zinc, 0.0125 to 0.05 part of vitamin A, 1.875 to 7.5 parts of vitamin C, 0.25 to 1 part of vitamin E, 3.75 to 15 parts of taurine and 0.75 to 3 parts of grape seed extract. The inventionprovides an application of the composition in the preparation of nutrients or medicines for enhancing immunity. According to the composition, the number of leukocytes and thymus indexes of mice subjected to chronic unpredictable stimulation are remarkably increased, C-reactive protein and glucocorticoid cortisol are remarkably reduced, immunoglobulin M and G are remarkably increased, and the cellular immune function, humoral immune function and mononuclear macrophage function are remarkably enhanced.

Description

technical field [0001] The invention relates to a functional composition, in particular to a composition and application for enhancing immunity. Background technique [0002] Studies have confirmed that chronic psychological stress factors such as long-term mental stress and depression can cause neuroendocrine disorders, resulting in a decline in the body's immune function, reducing the body's ability to fight infection, and the incidence of diseases will increase accordingly. Although great progress has been made in the research on the harm of chronic psychological stress, there is still a lack of effective intervention methods for its harm. Therefore, it is of great significance to study possible intervention strategies to enhance the immune system of people with depression and anxiety to improve the physical fitness of the people. At present, it is generally believed that the disorder of the neuro-endocrine-immune regulatory network is related to low immunity. Based on t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/87A61P37/04A23L33/105A23L33/16A23L33/15A23L33/155A23L33/175A61K33/30A61K31/07A61K31/375A61K31/355A61K31/185
CPCA23V2002/00A61K31/07A61K31/185A61K31/355A61K31/375A61K33/30A61K36/87A23L33/105A23L33/15A23L33/155A23L33/16A23L33/175A61P37/04A61K2300/00A23V2200/324A23V2250/0644A23V2250/1642A23V2250/702A23V2250/708A23V2250/712
Inventor 虞立霞洪燕袭著革彭晖李超付波魏爱丽
Owner INST OF ENVIRONMENTAL MEDICINE & OCCUPATIONAL MEDICINE ACAD OF MILITARY MEDICINE ACAD OF MILITARY SCI
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