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High-resolution time-of-flight mass spectrometer

A time-of-flight and mass spectrometer technology, applied in the field of mass spectrometry, can solve the problems of weak particle signal, unreachable, lack of particle mass screening and particle focusing functions, etc., and achieve the effect of high-precision mass spectrometry imaging

Active Publication Date: 2021-02-12
EAST CHINA NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the existing time-of-flight mass spectrometers do not have the functions of particle mass screening and particle focusing, resulting in excessive background noise of the mass spectrum and obliterating weaker particle signals
Moreover, in order to prevent the loss of particles caused by particle divergence, the existing time-of-flight mass spectrometer has a short field-free flight area, which cannot achieve high resolution

Method used

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Examples

Experimental program
Comparison scheme
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Embodiment

[0043] In this embodiment, the particle beam source is selected as an electrospray ionization source;

[0044] refer to figure 1 , figure 2 , the accelerating electrode 2 is made up of a tubular pipeline accelerating electrode 21, a disc-shaped ring-shaped accelerating electrode 22 and a ring-shaped grounding electrode 23. The diameter of the aperture is 10 mm, the diameter of the disk-shaped accelerating electrode 22 is 14 mm, and the diameter of the disk-shaped ground electrode 23 is 21 mm.

[0045] Voltage setting: -1000V for the pipeline accelerating electrode 21, -871V for the disc-shaped ring-shaped accelerating electrode 22, and 0V for the ring-shaped ground electrode 23.

[0046] refer to figure 1 , image 3 , Figure 4 , the first-stage focusing prism 3 is the same as the second-stage focusing prism 6, and is composed of a quadrupole ion deflection channel 31 and an ion focusing prism electrode group 32, wherein the ion focusing electrode group 32 is composed of...

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Abstract

The invention discloses a mass spectrometer with high-resolution flight time. The mass spectrometer comprises a vacuum cavity, an acceleration electrode, a first-stage focusing prism, an X-Y deflection device, an ion flight tube, a second-stage focusing prism, a mass selection device, a momentum speed reducer and a detector, according to the device, charged particles are radially focused through the focusing prism, so that particle loss caused by diffusion is reduced; high-precision mass selection is carried out on the charged particles through a mass selection device, and impurity particles are screened out to achieve high-precision mass spectrum imaging; ions or charged clusters are decelerated in the axial direction through a momentum decelerator, and the Doppler broadening effect caused by momentum is reduced. Through focusing, screening and decelerating, the detection resolution and efficiency of the mass spectrometer can be greatly improved.

Description

technical field [0001] The invention relates to the technical field of mass spectrometry, in particular to a high-resolution time-of-flight mass spectrometer. Background technique [0002] Time-of-flight mass spectrometry is a widely used mass spectrometry technique. Due to its advantages of high sensitivity, high resolution, and wide imaging range, it has a very broad application in the fields of atmospheric environment science, energy science, life and health science, and medicinal chemistry. Application scenarios. Usually, time-of-flight mass spectrometers are used to analyze charged particles such as ions or ion clusters. ) etc., after passing through a field-free flight zone, particles with different mass-to-charge ratios have different flight speeds, and the time required to pass through the same flight path is different. The detector can judge the particle’s The mass-to-charge ratio can then be used for qualitative analysis of particles. However, most of the existi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): H01J49/40H01J49/16
CPCH01J49/165H01J49/40
Inventor 王鹏昭杨岩刘博通唐鹏杨帆蒋延荣孙海涛张诗按孙真荣
Owner EAST CHINA NORMAL UNIV
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