Composition for promoting angiogenesis around hair follicles and/or promoting hair growth and application
An angiogenesis and hair growth technology, applied in the field of medical cosmetology, to achieve the effects of promoting hair growth, improving hair loss symptoms, and improving blood flow supply to hair follicles
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[0079] The present invention also provides a preparation method of the above-mentioned composition for promoting perifollicular angiogenesis and / or hair growth, comprising: preparing an aqueous solution containing Chinese medicine extract; preparing a solution containing copper element; adding the aqueous solution containing Chinese medicine extract to It is mixed with a solution containing copper element, and the filtrate is collected by filtering and sterilizing to obtain a composition for promoting perifollicular angiogenesis and / or hair growth, and the raw materials of the traditional Chinese medicine extract include Panax notoginseng and Salvia miltiorrhiza.
[0080] Among them, the present invention has no special limitation on the sources of all raw materials, which can be commercially available.
[0081] In the present invention, the preparation method of the traditional Chinese medicine extract is the same as that described above, and will not be repeated here.
[008...
Embodiment 1
[0093] After pulverizing 90g of Danshen medicinal material and 17.6g of Sanqi medicinal material, add it to the extraction tank, add 5 times the amount of water, decoct at 90°C for 2 hours, filter, and extract the filter residue for the second time, add 4 times the amount of water, and decoct at 90°C Boil for 1 hour, filter, discard the filter residue, and combine the filtrate. The filtrate is concentrated under reduced pressure until the volume of the medicinal solution and the weight ratio of the medicinal material are 1L: (0.9-1.1) kg, slowly add 95% ethanol to make the alcohol concentration of the medicinal solution 69%-71%, and let it stand for 12 hours. Take the supernatant of the medicinal solution after alcohol precipitation, filter, recover ethanol from the filtrate, concentrate it into an extract with a relative density of 1.38 (55° C. to 60° C.), and obtain a traditional Chinese medicine extract.
Embodiment 2
[0095] 2.1 Take 90g of the pulverized Danshen medicinal material and add it to the extraction tank, add 5 times the amount of water, decoct at 90°C for 2 hours, filter, and extract the filter residue for the second time, add 4 times the amount of water, and decoct at 90°C for 1 hour, Filtrate, discard the filter residue, combine the filtrate, concentrate the filtrate under reduced pressure until the volume of the medicinal solution and the weight ratio of the medicinal material are 1L: (0.9-1.1) kg, slowly add 95% ethanol, so that the alcohol concentration of the medicinal solution is 69%- 71%, stand for 12h. Take the supernatant of the medicinal solution after alcohol precipitation, filter it, recover ethanol from the filtrate, and concentrate it into an extract with a relative density of 1.38 (55° C. to 60° C.) to obtain the salvia miltiorrhiza extract.
[0096] 2.2 Add 17.6g of crushed Panax notoginseng to the extraction tank, add 5 times the amount of water, decoct at 90°C...
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