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Traditional Chinese medicine composition and application thereof in preparation of traditional Chinese medicine preparation for treating osteoporosis

A technology of traditional Chinese medicine preparations and compositions, applied in the field of traditional Chinese medicine compositions, can solve the problems of Dabushen Decoction with many cold and greasy medicinal flavors, insufficient power of warming yang to transform qi, easy damage to spleen and stomach yang, and so on, so as to improve bone biomechanics , Improve osteoporosis and inhibit bone resorption

Active Publication Date: 2020-10-13
李鼎鹏 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

"Da Bushen Decoction provides a good reference for traditional Chinese medicine to treat osteoporosis through tonifying kidney essence, but Da Bushen Decoction has a wide range of indications, and there are still some limitations and deficiencies in the treatment of osteoporosis, mainly: osteoporosis and kidney deficiency The pathogenesis is the main line, and the kidney is used as the main method to send prescriptions and medicines. In clinical practice, the pathogenesis of osteoporosis has different syndromes, such as deficiency of kidney yang, deficiency of kidney yin, and deficiency of both yin and yang. Bushen Decoction is mainly composed of traditional Chinese medicines for nourishing yin and nourishing kidney. It has a strong effect of nourishing yin and reducing fire, but the power of warming yang and transforming qi is insufficient. At the same time, Dabushen Decoction has too much taste of cold and greasy medicine. Long-term use of the medicine will easily nourish and hinder the stomach. Excessive cold and cool can easily damage the yang qi of the spleen and stomach, which will intensify the imbalance of yin and yang in the kidneys. Therefore, Dabushen decoction is mainly used to nourish the kidney and replenish essence, and at the same time, dialectical addition and subtraction should be combined with the differences in yin and yang of the five internal organs.

Method used

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  • Traditional Chinese medicine composition and application thereof in preparation of traditional Chinese medicine preparation for treating osteoporosis
  • Traditional Chinese medicine composition and application thereof in preparation of traditional Chinese medicine preparation for treating osteoporosis
  • Traditional Chinese medicine composition and application thereof in preparation of traditional Chinese medicine preparation for treating osteoporosis

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Experimental program
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Effect test

Embodiment 1

[0016] Application of a traditional Chinese medicine composition in the preparation of a traditional Chinese medicine preparation for treating osteoporosis, wherein the traditional Chinese medicine composition is prepared from the following raw materials: 25g of rehmannia glutinosa, 20g of bamboo leaves, 15g of licorice, 15g of Eucommia ulmoides, 10g of drynariae, Knee 10g, Psoralen 10g, Guizhi 10g, Dried Ginger 10g, Epimedium 10g, Cistanche 10g, Schisandra 10g, Alisma 10g.

[0017] Clinical validation:

[0018] 1. Case selection: 120 outpatients with osteoporosis in Gansu Hospital of Traditional Chinese Medicine were selected, including 63 males and 57 females; aged 55-85 years. They were randomly divided into control group and experimental group, 60 cases in each group. There was no significant difference between the two groups in age, height, weight and other baseline data ( P >0.05), comparable.

[0019] The diagnostic criteria refer to the standards of the World Health...

Embodiment 2

[0035]Application of a traditional Chinese medicine composition in the preparation of a traditional Chinese medicine preparation for treating osteoporosis, wherein the traditional Chinese medicine composition is prepared from the following raw materials: rehmannia glutinosa 35g, bamboo leaves 30g, licorice 25g, Eucommia ulmoides 25g, drynaria rhizome 20g, bovine Knee 20g, Psoralen 20g, Guizhi 20g, Dried Ginger 20g, Epimedium 20g, Cistanche 20g, Schisandra 20g, Alisma 20g.

Embodiment 3

[0037] Application of a traditional Chinese medicine composition in the preparation of a traditional Chinese medicine preparation for treating osteoporosis, wherein the traditional Chinese medicine composition is prepared from the following raw materials: Rehmannia glutinosa 30g, bamboo leaves 25g, licorice 20g, Eucommia ulmoides 20g, Drynaria rhizome 15g, bovine Knee 15g, Psoralen 15g, Guizhi 15g, Dried Ginger 15g, Epimedium 15g, Cistanche 15g, Schisandra 15g, Alisma 15g.

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Abstract

A traditional Chinese medicine composition is prepared from the following raw material: rehmannia, bamboo leaves, liquorice, eucommia ulmoides, rhizoma drynariae, radix achyranthis bidentatae, fructuspsoraleae, cassia twig, dried ginger, herba epimedii, herba cistanche, schisandra chinensis and rhizoma alismatis. The invention further provides application of the traditional Chinese medicine composition in preparation of a traditional Chinese medicine preparation for treating osteoporosis. The traditional Chinese medicine composition and the traditional Chinese medicine preparation for treatment osteoporosis have the beneficial effects that pathology can be carried out on treatment mechanisms of osteoporosis, kidney essence deficiency, kidney qi deficiency, kidney yang deficiency and kidney yin deficiency, and the traditional Chinese medicine composition and the traditional Chinese medicine preparation are suitable for osteoporosis of various traditional Chinese medicine syndrome types; the traditional Chinese medicine composition is mainly suitable for treating symptoms such as waist and knee aching pain, muscle and bone weakness, muscle and bone weakness, waist and knee pain, walking failure, dizziness, deficiency-heat rushing adverse flow, difficult urination and weak pulse; modern medical research finds that the formula has the effects of improving osteoporosis, increasingthe bone mineral content, improving bone biomechanics, promoting bone formation, inhibiting bone resorption and reducing the high conversion state of bones.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition and its application in preparing traditional Chinese medicine preparations for treating osteoporosis. Background technique [0002] Osteoporosis belongs to the category of "bone impotence" and "bone dryness" in traditional Chinese medicine. Traditional Chinese medicine believes that this disease is mostly caused by insufficient congenital endowment, lack of recuperation the day after tomorrow, long-term illness without treatment, and aging. The pathogenesis is mainly kidney deficiency, spleen deficiency, blood stasis and so on. As early as in the Huangdi Neijing "Suwen impotence theory", it is recorded: "If the kidney qi is hot, the waist and spine will not move, the bones will dry up and the marrow will decrease, and the hair will become bone impotence." That is, bone flaccidity is caused by kidney de...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P19/10
CPCA61K36/804A61K36/899A61K36/484A61K36/46A61K36/126A61K36/21A61K36/487A61K36/54A61K36/9068A61K36/296A61K36/64A61K36/79A61K36/57A61K36/884A61P19/10A61K2300/00
Inventor 李鼎鹏谢兴文郑先丽
Owner 李鼎鹏
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