Traditional Chinese medicine for treating intrahepatic cholestatic liver diseases of infants based on hepatic collateral disease theory

Abstract

The invention relates to a traditional Chinese medicine for treating intrahepatic cholestatic hepatopathy of infants based on a hepatic collateral disease theory, which takes peach kernel, safflower,radix paeoniae rubra and herba lycopi as monarch drugs and is mainly used for promoting blood circulation to remove blood stasis and removing hepatic collateral stasis; radix bupleuri, radix curcumae,ligusticum wallichii and fructus aurantii are used as ministerial drugs to soothe liver, promote qi circulation and smooth liver collaterals and qi stagnation, angelica sinensis and radix rehmanniaeare used as adjuvant drugs to nourish and tonify blood, raw malt, bighead atractylodes rhizome and oriental wormwood soothe liver, raise stomach qi, invigorate spleen, eliminate dampness and harmonizestomach, and achyranthes bidentata is combined to activate blood and nourish liver collaterals. The traditional Chinese medicine disclosed by the invention has the advantages that laboratory indexessuch as liver function and clinical indexes such as cholestasis and blood coagulation functions are remarkably improved, the clinical total effective rate of treating the intrahepatic cholestatic liver disease of infants is superior to that of the existing western medicines such as ursodeoxycholic acid, and the traditional Chinese medicine has the advantages of good compliance, small dosage, quickresponse, few side effects and the like.

Description

technical field [0001] The invention relates to a traditional Chinese medicine for treating infant intrahepatic cholestasis liver disease based on liver collateral disease theory, belonging to the field of traditional Chinese medicine application. Background technique [0002] Infant cholestatic liver disease is a common disease in infant liver disease, and has become the first hospitalization cause of liver disease in children in China. If the cholestasis persists and is not relieved, it can accelerate liver cell damage and develop into liver fibrosis and cirrhosis as the disease progresses, endangering the health and life of the children. Cholestasis is generally divided into intrahepatic cholestasis and extrahepatic cholestasis. The causes of intrahepatic cholestasis are complex and related to premature birth, infection, genetic metabolism and other factors. Western medicine mainly focuses on symptomatic treatment, and there is no specific treatment. Liver transplantati...

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Problems solved by technology

At present, there are no reports of drugs for the treatment of infant liver disease based on the theory of liver collateral disease

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