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Sodium hyaluronate dressing containing icodextrin

A technology of sodium hyaluronate and icodextrin, which is applied in bandages, medical science and other directions, can solve the problems of restricting the use of sodium hyaluronate and unsatisfactory effects for consumers, and achieves reduced skin burden and good smoothness. , the effect of accelerating metabolism

Inactive Publication Date: 2020-09-11
HUAREN PHARMACEUTICAL CO LTD +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, sodium hyaluronate has the highest moisture absorption at low relative humidity (33%), and the lowest moisture absorption at high relative humidity (75%). This property makes sodium hyaluronate products only available in fixed seasons. Good results only in certain areas, so that consumers can not get satisfactory results, which limits the use of sodium hyaluronate

Method used

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  • Sodium hyaluronate dressing containing icodextrin
  • Sodium hyaluronate dressing containing icodextrin
  • Sodium hyaluronate dressing containing icodextrin

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Icodextrin 0.008%, Sodium Hyaluronate 0.08%, Propylene Glycol 3.6%, Chlorphenesin 0.05%, Phenoxyethanol 0.3%, Ethylhexylglycerin 0.5%, 1,2-Hexanediol 0.5%, Purified Water 94.96%, neroli essential oil 0.002%.

Embodiment 2

[0027] Icodextrin 0.45%, Sodium Hyaluronate 0.1%, Propylene Glycol 4.5%, Chlorphenesin 0.06%, Phenoxyethanol 0.45%, Ethylhexylglycerin 0.1%, 1,2-Hexanediol 0.4%, Purified Water Or water for injection 93.937%, neroli essential oil 0.003%.

Embodiment 3

[0029] Icodextrin 0.03%, Sodium Hyaluronate 0.6%, Propylene Glycol 4.2%, Chlorphenesin 0.08%, Phenoxyethanol 0.44%, Ethylhexylglycerin 0.3%, 1,2-Hexanediol 0.3%, Purified Water Or water for injection 94.048%, rose essential oil 0.002%.

[0030] (1) The film-forming effect of the above-mentioned examples was tested, and the obtained examples all had good air permeability after film-forming, and the data obtained from the tensile test were:

[0031] Example 1 Example 2 Example 3 Tensile capacity / MPa 2.64 2.73 3.1

[0032] From Figure 1-3 It can be seen that the obtained dressing has uniform pores after film formation, has high porosity, and has good air permeability during application.

[0033] (2) Collagen dressings containing icodextrin (each dressing contains 10 g of the composition in the example) prepared by the above-mentioned examples and gauze by common preparation methods were applied to 3 subjects who had undergone microneedling cosmetic ...

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Abstract

The invention provides a sodium hyaluronate dressing containing icodextrin. The sodium hyaluronate dressing comprises the following components in parts by mass: 0.008-0.05% of icodextrin, 0.05-0.1% ofsodium hyaluronate, 3-6% of propylene glycol, 0.02-0.1% of chlorophenyl glycol, 0.3-0.5% of phenoxyethanol, 0.1-0.5% of ethylhexyl glycerin, 0.3-0.5% of 1,2-hexanediol, 93-95% of purified water or water for injection, and 0.001-0.005% of flavoring agent. The dressing of the present invention has a good moisturizing and repairing effect, can be made into a form of original liquid + gauze / non-wovenfabric, has good nutrition and lubrication effect on skin, and especially can make damaged skin recover faster, so that the skin is less prone to proliferation or pollution.

Description

technical field [0001] The invention belongs to the field of medical devices, in particular to a sodium hyaluronate dressing containing icodextrin. Background technique [0002] Sodium hyaluronate is a mucopolysaccharide formed by alternately linking glucuronic acid and N-acetylglucosamine as disaccharide units. It is widely found in nerve tissue, skin dermis and other tissues; in organs, it is distributed in the cytoplasm, intercellular substance It lubricates and nourishes the cells and organelles contained therein. [0003] Glucan is a homopolysaccharide composed of glucose as a monosaccharide, which is divided into α-glucan and β-glucan, and each glucan has a variety of bond combinations. As an active ingredient in skin care products, dextran has a long history in the West. Families in many European and American countries are used to bathing infants and young children with water soaked in oatmeal to relieve and prevent eczema; the elderly are also used to washing their...

Claims

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Application Information

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IPC IPC(8): A61L26/00
CPCA61L26/0023A61L26/0061A61L26/0057C08L3/02C08L5/08
Inventor 杨效东王盈盈冯新光班文溥逄婧衣思闻
Owner HUAREN PHARMACEUTICAL CO LTD
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