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Traditional Chinese medicine composition for treating cesarean scar pregnancy and applications thereof

A uterine pregnancy and composition technology, applied in the field of medicine, can solve the problems of inability to remove gestational sac residues, poor clinical effect, and long time to return to normal values, so as to shorten vaginal bleeding time, remove gestational sac residues, reduce Effects of Complications

Active Publication Date: 2020-08-28
合肥市第三人民医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, clinical application of UAE+ curettage in the treatment of CSP often finds that the residual gestational sac cannot be completely removed, and it takes a long time for the patient’s blood β-HCG (human chorionic gonadotropin) to return to normal, which means that the residual gestational sac still has certain activity
In view of the above situation, Chinese patent medicines such as Xinhua Granules [ingredients are: angelica, Chuanxiong, peach kernel, roasted licorice, dried ginger (charcoal), motherwort, safflower] are often used in combination for treatment, but the clinical effect is poor (following examples A controlled study will be conducted)
At the same time, in the existing literature, there is no combination of traditional Chinese medicine prescriptions combined with UAE+uterine curettage for the treatment of CSP, only treatment schemes such as Chinese medicine prescriptions combined with mifepristone+MTX (the following examples will be discussed in comparison with the existing open literature)

Method used

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  • Traditional Chinese medicine composition for treating cesarean scar pregnancy and applications thereof
  • Traditional Chinese medicine composition for treating cesarean scar pregnancy and applications thereof
  • Traditional Chinese medicine composition for treating cesarean scar pregnancy and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] The Chinese medicine decoction that is used for the treatment of scar uterine pregnancy of the present embodiment is made up of the component of following weight:

[0018] Fritillaria 10g, Prunella vulgaris 15g, Smilax tuckahoe 15g, peach kernel 10g, safflower 10g, rehmannia glutinosa 10g, chuanxiong 6g, angelica 10g, red peony 10g, Chuan Achyranthes bidentata 10g, trichosanthes 10g, licorice 3g.

[0019] The traditional Chinese medicine decoction of the present embodiment is made by adding water and decocting conventionally in the art.

Embodiment 2

[0021] The Chinese medicine decoction that is used for the treatment of scar uterine pregnancy of the present embodiment is made up of the component of following weight (compared with embodiment 1, difference is only: Smilax smilax 20g):

[0022] Fritillaria 10g, Prunella vulgaris 15g, Smilax tuckahoe 20g, peach kernel 10g, safflower 10g, Rehmannia glutinosa 10g, Chuanxiong 6g, Angelica 10g, Chishao 10g, Achyranthes bidentata 10g, Trichosanthes 10g, 3g licorice.

Embodiment 3

[0024] The Chinese medicine decoction for the treatment of scarred uterine pregnancy of the present embodiment is made up of the component of following weight (compared with embodiment 1, difference is only: Fritillaria japonicus 13g, Prunella vulgaris 20g):

[0025] Fritillaria 13g, Prunella vulgaris 20g, Smilax 15g, peach kernel 10g, safflower 10g, Rehmannia glutinosa 10g, Chuanxiong 6g, Angelica 10g, Chishao 10g, Achyranthes bidentata 10g, Trichosanthes 10g, licorice 3g.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating cesarean scar pregnancy. The medicament prepared from, by weight ratio, 10 parts of bulbus fritillariae thunbergii, 15 parts of common selfheal fruit-spike, 15 parts of glabrous greenbrier rhizome, 10 parts of peach seeds, 10 parts of safflower, 10 parts of prepared rehmannia roots, 6 parts of Sichuan lovage rhizome, 10 parts of Chinese angelica, 10 parts of red peony roots, 10 parts of medicinal cyathula roots, 10 parts of snakegourd roots and 3 parts of liquorice roots. The traditional Chinese medicine composition has the main effects of dispersing concretions, killing embryo and resolving hard lump, and is supplemented by selecting multiple components having the efficacy of improving blood circulation and disperse stasis. When the traditional Chinese medicine composition is used for treating CSP by combining with UAE and complete curettage of uterine cavity, gestational sac residuals can be completely eliminated, vaginal bleeding time can be shortened, treatment effects can be further enhanced, and the occurrence of complications can be reduced.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine composition for treating scarred uterine pregnancy, and the Chinese medicine composition combined with uterine artery embolization and uterine curettage is applied to treat scarred uterine pregnancy. Background technique [0002] Cesarean scar pregnancy (CSP), also known as cesarean scar pregnancy, refers to the implantation of embryos in the cesarean scar, which is a special site of ectopic pregnancy. In recent years, with the opening of the two-child policy and the high rate of cesarean section, the probability of CSP has increased significantly compared with the past. The etiology of CSP may be related to poor scar healing, which can lead to serious complications of uterine rupture and hemorrhage. Therefore, timely termination of pregnancy treatment is required. [0003] At present, there are mainly the following clinical methods f...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61K36/8966A61P15/00
CPCA61K36/8966A61K36/536A61K36/90A61K36/896A61K36/736A61K36/286A61K36/804A61K36/236A61K36/232A61K36/71A61K36/65A61K36/21A61K36/428A61K36/484A61P15/00A61K2300/00Y02A50/30
Inventor 刘汉顺徐鹏
Owner 合肥市第三人民医院
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