Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Comprehensive utilization method of immature bitter oranges

A Citrus aurantium and compound enzyme technology, applied in chemical instruments and methods, preparation of sugar derivatives, sugar derivatives, etc., can solve the problems of long extraction time, environmental pollution, and low extraction efficiency, and reduce extraction time and solvent. The effect of dosage and reduction of production cost

Active Publication Date: 2020-04-24
CHONGQING HOLLEY PHARMA
View PDF6 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the process is simple, the extraction time required for extraction using a mixed solution of methanol and alkali is relatively long, the amount of solvent required is large, and the extraction efficiency is not high
In addition, if the medicinal material of Citrus aurantium is exposed to the mixed solution of methanol and alkali for a long time, the functional components or valuable components in the medicinal material (drug residue) will be destroyed, and the extracted medicinal residue cannot be reused and can only be discarded.
And a large amount of discarded medicinal residues with a large amount of solvent will cause very serious pollution to the environment

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1: Hesperidin extraction example

[0036] Get fresh Fructus Fructus Aurantii, cross 15 mesh sieves after pulverizing, obtain Fructus Fructus Fructus Fructus Raw Material, the weight of Fructus Fructus Fructus Fructus Fructus Raw Material is 100kg.

[0037] (1) The first enzymolysis treatment: put the Fructus Aurantium raw material into the enzymolysis tank, add water to the Fructus Fructus Fructus raw material, the dosage ratio of the Fructus Fructus Fructus Fructus raw material and water is 1kg: 1L, then add compound enzyme I in the water, compound The concentration of enzyme I was 0.6g / L. The duration of compound enzyme Ⅰ enzymatic hydrolysis treatment of Fructus Aurantii raw material was 2 hours, the temperature was 35 ℃, and the pH value was 6.5. In compound enzyme Ⅰ, the mass ratio of cellulase, hemicellulase and pectinase is 1:1:3. Obtained after the completion of enzymatic hydrolysis, the raw material Ⅰ of Citrus aurantium enzymolysis.

[0038] (2) ...

Embodiment 2

[0041] Embodiment 2: Hesperidin extraction example

[0042] Get fresh citrus aurantium, cross 15 mesh sieves after pulverizing, obtain citrus aurantium raw material, the weight of citrus aurantium raw material is 200kg.

[0043](1) The first enzymolysis treatment: put the Fructus Aurantium raw material into the enzymolysis tank, add water to the Fructus Fructus Fructus raw material, the dosage ratio of the Fructus Fructus Fructus Fructus raw material and water is 1kg: 1L, then add compound enzyme I in the water, compound The concentration of enzyme I was 1.0 g / L. The duration of compound enzyme Ⅰ enzymatic hydrolysis treatment of Fructus Aurantii raw material was 2 hours, the temperature was 37 ℃, and the pH value was 7.0. In compound enzyme Ⅰ, the mass ratio of cellulase, hemicellulase and pectinase is 1:1:3. Obtained after the completion of enzymatic hydrolysis, enzymatic hydrolysis of citrus citrus raw material I.

[0044] (2) The second enzymatic hydrolysis treatment: A...

Embodiment 3

[0047] Embodiment 3: hesperidin extraction example

[0048] Get fresh citrus aurantium, cross 15 mesh sieves after pulverizing, obtain citrus aurantium raw material, the weight of citrus aurantium raw material is 350kg.

[0049] (1) The first enzymolysis treatment: put the Fructus Aurantium raw material into the enzymolysis tank, add water to the Fructus Fructus Fructus raw material, the dosage ratio of the Fructus Fructus Fructus Fructus raw material and water is 1kg: 2L, then add compound enzyme I in the water, compound The concentration of enzyme I was 1.2g / L. The duration of compound enzyme Ⅰ enzymatic hydrolysis treatment of Fructus Aurantii raw material was 3 hours, the temperature was 45 ℃, and the pH value was 7.5. In compound enzyme Ⅰ, the mass ratio of cellulase, hemicellulase and pectinase is 1:2:4. Obtained after the completion of enzymatic hydrolysis, enzymatic hydrolysis of citrus citrus raw material I.

[0050] (2) The second enzymatic hydrolysis treatment: A...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the field of natural product preparation, and relates to a comprehensive utilization method of immature bitter oranges. According to the method, the step of enzymolysis pretreatment is added, so that the hesperidin extraction efficiency is improved, the extraction time is shortened, and the amount of an extraction solvent is reduced, the damage to functional components inthe long-time extraction process is avoided, and the comprehensive utilization of immature bitter oranges can be realized. The comprehensive utilization method can be applied to production practice ofextraction of hesperidin, the extraction rate and purity of hesperidin are improved, and the comprehensive utilization rate of the raw material immature bitter oranges is further guaranteed.

Description

technical field [0001] The invention relates to the field of natural product preparation, and relates to a comprehensive utilization method of citrus aurantii. Background technique [0002] Citrus aurantium is the young fruit of Citrus aurantium L., a Rutaceae plant, which has the effect of reducing Qi and eliminating stagnation, and has high medicinal value. Citrus aurantium contains components such as hesperidin, neohesperidin, naringin, synephrine and N-methyltyramine, among which hesperidin Glycoside content is the highest. Hesperidin, also known as nobietin and dihydroflavone glucoside, can be used as a vitamin drug, which can reduce the fragility of capillaries, protect capillaries, prevent capillary rupture and bleeding, and can be used as an adjuvant treatment for hypertension. Due to the large content of hesperidin in Fructus Aurantium, Fructus Aurantium is often used as a raw material for hesperidin extraction. [0003] Chinese patent CN103467546A (a production ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07H17/07C07H1/08
CPCC07H17/07C07H1/08
Inventor 石磊张文平杨婷
Owner CHONGQING HOLLEY PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com