Animal solid soft chewing nutritional preparation and preparation method thereof

Abstract

The invention provides an animal solid soft chewing nutritional preparation and a preparation method thereof. The animal solid soft chewing nutritional preparation is characterized by comprising the following raw materials by mass: 15-50% of a binder, 5-15% of a disintegrating agent, 10-20% of a corrigent, 10-20% of a wetting agent, 20-45% of a filler, 3-15% of an active ingredient, 0.1-0.15% of apreservative, 0.01-0.1% of an antioxidant and water which makes up the remaining mass. Through the binder, the animal solid soft chewing nutritional preparation has viscosity and can be compression-molded. Through the disintegrating agent, the absorptivity of animals to the animal soft chewing nutritional preparation is improved while the viscosity is enhanced. The filler and the corrigent are added to enable the fragrance and taste of food to have certain allure to pets while enhancing the nutrition of animals and improving the immunity of the animals. The active ingredient is a traditionalChinese medicine ingredient and can be used for providing a medicine effect and achieving a treatment effect on various diseases of animals. Therefore, a medicine can be made into edible soft chewablefood in the form of meat-like blocks, and the palatability of the medicine to animals is improved.

Description

technical field [0001] The invention belongs to the field of animal nutrition products, in particular to a solid soft chewing nutrition preparation for animals and a preparation method thereof. Background technique [0002] The palatability of drugs can increase the patient acceptance of drugs, especially for animals, and cats among animals are more picky about the palatability of drugs. Animals tend to swallow solid preparations in the form of tablets or capsules, but many active substances The mouthfeel itself is extremely bad (as bitter taste, astringent taste, etc.), which makes the palatability of animals very poor when taking medicine. Flavoring, flavoring or palatable agents are used to improve the palatability of pharmaceutical formulations. For example, animal-derived flavoring agents (such as beef powder, chicken liver powder, pork powder, beef bone powder, liver powder, milk, gelatin, eggs, etc.) or vegetable-derived flavoring agents (such as soybean protein, etc...

AI Technical Summary

Problems solved by technology

[0003] Chinese patent CN105963270A discloses a soft chewable tablet of benazepril hydrochloride and its preparation method. In this patent, the ratio of the coating material and the raw material drug in this patent cannot achieve a good taste-masking effect at all.

Chinese patent CN100488376C discloses a palatable plastic chewable veterinary composition, that is, the corresponding Interceptor Plus, the active ingredient of this patent is an insect repellent (in vivo and in vitro), and it has high requirements for extrusion equipment (at least Buhler BCTG -62 / 28D model and above), and it is required to be extruded at low temperature (less than 10°C). This patented method undoubtedly increases the production cost, and is not conducive to large-scale production and popularization in China.

Chinese patent CN101909605B discloses a method for manufacturing a soft chewable dosage form for drug delivery and its products. This patent also mentions the need for fluidized bed coating of raw materials. This patent method increases production costs and requires equipment performance High, not suitable for large-scale production and promotion in China

[0005] However, heat of compression is generated during this process, making this method unsuitable for compounds with low melting points and affecting formulation uniformity, consistency, and stability

Moreover, none of the equipment used in the production process of the above-mentioned method is an industrialized equipment for drug production, or equipment with special requirements is used, such as low temperature is required, or special treatment (such as fluidized bed coating) is required for the raw material drug. , are not conducive to the realization of industrialized production of drugs