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External composition for preventing, relieving or treating skin allergy and application thereof

A topical composition and technology for skin allergies, applied in the field of topical compositions for prevention, antibacterial, relief or treatment of skin allergies, anti-inflammation, and anti-irritation. To achieve the effect of improving the skin epidermis, improving the vitality of skin cells, and accelerating regeneration

Inactive Publication Date: 2020-04-10
BLOOMAGE BIOTECHNOLOGY CORP LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] ①It cannot promote the repair of skin tissue cells to rebuild the skin barrier, but needs the body's own immune system and specific expression factors to rebuild the barrier
[0006] ②Using the above-mentioned preparations to treat skin barrier defect diseases usually has strong side effects and / or causes allergic reactions in the human body, such as skin erythema, acne, papules, skin itching, wound healing disorders and other reactions, and possible adverse reactions after use some symptoms of skin irritation
Although the above-mentioned traditional Chinese medicine composition has the advantages of anti-inflammatory, antipruritic, and pain-relieving effects while avoiding the side effects caused by conventional preparations to a certain extent, and has the advantages of being safe, mild, and non-toxic and side effects, the effect on rebuilding the skin barrier Not significant enough

Method used

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  • External composition for preventing, relieving or treating skin allergy and application thereof
  • External composition for preventing, relieving or treating skin allergy and application thereof
  • External composition for preventing, relieving or treating skin allergy and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] 0.1g ectoine, 20g sodium hyaluronate (molecular weight 1×10 3 Da), 5g surfactin, and 0.01gε-polylysine were dissolved in purified water and the volume was adjusted to 100mL, and mixed uniformly to prepare external composition 1 for preventing, alleviating or treating skin allergies.

Embodiment 2

[0063] 10g ectoine, 0.1g sodium hyaluronate (molecular weight 4×10 5 Da), 0.1g rhamnolipid, and 0.1gε-polylysine were dissolved in purified water and adjusted to 100mL, and mixed uniformly to prepare external composition 2 for preventing, alleviating or treating skin allergies.

Embodiment 3

[0065] 5g hydroxytetrahydropyrimidine, 10g acetylated hyaluronic acid (molecular weight 8×10 4 Da), 2g surfactin, 0.05gε-polylysine were dissolved in purified water and the volume was adjusted to 100mL, and mixed uniformly to make external composition 3 for preventing, alleviating or treating skin allergies.

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Abstract

The invention discloses an anti-inflammatory, antibacterial and anti-irritant external composition for effectively preventing, relieving or treating skin allergy, which is safe, environment-friendly,free of side effects and irritation. The composition comprises ectoine or a derivative thereof, hyaluronic acid or a derivative thereof, a biosurfactant, and epsilon-polylysine as a central composition, and optionally comprises one or more vitamins, and optionally comprises one or more natural plant ingredients. The composition is provided in the form of a cosmetic, a medical device, a medicine, or an additive to the foregoing product.

Description

technical field [0001] The invention belongs to the technical field of cosmetics and medicines, and in particular relates to an external composition for preventing, alleviating or treating skin allergy, anti-inflammation, antibacterial and anti-irritation and its application. Background technique [0002] The skin covers the surface of the human body and is the largest organ of the human body. It is in direct contact with the external environment, protecting various tissues and organs in the body from damage from mechanical, physical, chemical and biological factors, and at the same time preventing various nutrients, The loss of water and electrolytes acts as a barrier and plays an important role in maintaining the stability of the internal environment of the human body. The skin barrier is mainly composed of sebum membrane and stratum corneum. The sebum film is a transparent film covering the surface of the skin. It is mainly formed by the emulsification of sebum secreted ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/505A61K31/728A61K31/785A61K36/71A61K36/65A61K9/00A61K47/26A61K47/42A61P17/00A61P37/08A61P29/00A61P31/04A61P31/10A61P17/04A61P17/02A61K8/88A61K8/73A61K8/49A61K8/60A61K8/64A61Q19/00A61Q17/00A61Q19/02
CPCA61K8/4953A61K8/60A61K8/64A61K8/735A61K8/88A61K9/0014A61K31/505A61K31/728A61K31/785A61K36/28A61K36/288A61K36/484A61K36/65A61K36/71A61K47/26A61K47/42A61K2800/592A61K2800/5922A61Q17/005A61Q19/00A61Q19/02A61P17/00A61P17/02A61P17/04A61P29/00A61P31/04A61P31/10A61P37/08A61K2300/00
Inventor 王冠凤石艳丽董艳美钱晓路陈晨刘玉敏周雪李晓天郭学平
Owner BLOOMAGE BIOTECHNOLOGY CORP LTD
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