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Mouse head fixing device for magnetic resonance imaging and fixing method for mouse head fixing device

A magnetic resonance imaging and fixation device technology, which is applied in applications, veterinary instruments, and equipment for restraining animals, etc., can solve the problems of inability to ensure mouse head movement and difficulty in combining

Pending Publication Date: 2020-02-14
CENT FOR EXCELLENCE IN BRAIN SCI & INTELLIGENCE TECH CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] However, the inventors found that the existing fixation devices and fixation methods still have the disadvantages of being difficult to combine with magnetic resonance imaging and unable to ensure that the mouse's head movement is restricted when the mouse is awake.

Method used

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  • Mouse head fixing device for magnetic resonance imaging and fixing method for mouse head fixing device
  • Mouse head fixing device for magnetic resonance imaging and fixing method for mouse head fixing device
  • Mouse head fixing device for magnetic resonance imaging and fixing method for mouse head fixing device

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Embodiment Construction

[0035] A variety of different implementations or examples for implementing the described subject technical solutions are disclosed below. In order to simplify the disclosure, the following describes the specific examples of each component and arrangement, of course, these are only examples, not limiting the protection scope of the present invention. For example, the description that the first feature described later in the description is formed on or above the second feature may include an embodiment in which the first and second features are formed through direct contact, and may also include an embodiment in which the first and second features are formed between the first and second features. Embodiments of additional features such that there may be no direct relationship between the first and second features. Additionally, reference numerals and / or letters may be repeated in different instances in these disclosures. This repetition is for brevity and clarity and does not i...

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Abstract

The invention aims to provide a mouse head fixing device for magnetic resonance imaging, which can limit the moving and rotating range of the head of a sober mouse after being fixed, and aims to provide a method for fixing the mouse head, which adopts the mouse head fixing device. The mouse head fixing device for realizing the above purpose comprises a pair of grasping arms and a connecting part,wherein the connecting part is connected with the pair of the grasping arms; the connecting part comprises a boss which is protruded upwards in an arc shape from two ends to the center; one or more sides of the boss extend outwards in an arc shape and protruding manner in the width direction of the fixing device to form an arc-shaped surface; and the arc-shaped surface is a fixing surface which isin contact with the head of the mouse.

Description

technical field [0001] The invention relates to a mouse head fixation device for magnetic resonance imaging and a fixation method thereof. Background technique [0002] In clinical scientific research (such as models of chronic brain lesions and models of acute trauma), mice are often selected as model animals for fMRI experiments. However, no matter whether it is a study of mice in a non-task state or a task state, anesthesia was often used in the past, mainly because the fMRI signal is easily affected by head movement, and the anesthesia method can control the head movement of mice at an ideal scale Inside. However, the state of anesthesia will inevitably change the activity level of the whole brain. On the one hand, the signal-to-noise ratio of the obtained image is low (the change of blood oxygen in the suppressed state is small), and on the other hand, the results from different researchers are difficult to compare (due to different anesthetic drugs and concentration...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/055A61D3/00
CPCA61D3/00A61D2003/003A61B5/055
Inventor 李澄宇韩哲
Owner CENT FOR EXCELLENCE IN BRAIN SCI & INTELLIGENCE TECH CHINESE ACAD OF SCI
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