Negative pressure skin penetration administration instrument and using method thereof

Abstract

The invention discloses a negative pressure skin penetration administration instrument and a using method thereof, and relates to the technical field of skin penetration administration. The negative pressure skin penetration administration instrument comprises an administration instrument box body, a power source interface and an external-connected administration end, wherein the power source interface is formed in the administration instrument box body; and the external-connected administration end is connected to the administration instrument box body. The negative pressure skin penetrationadministration instrument also comprises an electricity leak protecting machine, a vacuum display gauge, a time display gauge, a vacuum pump, a vacuity regulating device, a time regulating device, a control circuit board, a vacuum exhaust adjusting valve and a vacuum output opening. According to the negative pressure skin penetration administration instrument disclosed by the invention, the opening and the closing of the vacuum pump and the closing and opening of the vacuum pumping adjusting valve are controlled and adjusted by a time relay through a circuit under the situation of negative pressure, so that the size of negative pressure is adjusted, the form of the skin is continuously changed under the effect of different vacuity, pores and tissue gaps of the skin are continuously enlarged and contracted, the breathe effect of the skin is generated, and medicines can better enter the skin to be absorbed by the human body.

Description

technical field [0001] The invention relates to the technical field of transdermal drug delivery, and more specifically relates to a negative pressure transdermal drug delivery device and a method for using the same. Background technique [0002] The concept of "transdermal technology" was first proposed by the United States in 1974. The so-called transdermal technology (transdermal therapeutic systems, TTS) is a new way of non-invasive drug delivery, which refers to drug delivery on the surface of the skin, so that the drug can pass through all layers of the skin. The method of entering the human body and circulatory system to produce systemic or local therapeutic effects is an important breakthrough in the traditional concept of skin medicine, and the research in this new field is very active at present. [0003] Compared with other drug delivery methods, the transdermal drug delivery technology has its unique advantages. The advantages are as follows: firstly, the transde...

AI Technical Summary

Problems solved by technology

Negative pressure in the negative pressure drug delivery technology is to make the skin and body tissues locally swell, and open the dermis, epidermis, capillaries and pores through negative pressure to open the pores and skin, so that the skin surface area increases and the skin tissue The gap increases, thereby reducing the barrier of drug transdermal, increasing the area of ​​the skin to absorb and infiltrate the drug, but the actual effect of the above methods is not ideal, and there are limitations in practical applications. Directly connecting the negative pressure to the skin is the Open the skin gap under negative pressure to allow the drug to enter the skin, but the skin is taut when it is in an open state under negative pressure, and the amount of drug entering is small. Another method is to apply positive pressure to the skin under negative pressure. Because the skin is also in a tense state under negative pressure, applying positive pressure under negative pressure is also not effective.

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