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Zhuang medicine preparation for preventing and treating hyperuricemia and preparation method thereof

A technology for hyperuricemia and preparations, which can be used in pharmaceutical formulations, medical preparations containing active ingredients, and drug combinations, etc., can solve problems such as high price and many side effects, and achieve low price, clever raw material ratio, and curative effect advantages. obvious effect

Active Publication Date: 2020-02-04
滕红丽
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For this reason, promoting uric acid excretion and at the same time inhibiting uric acid synthesis to reduce blood uric acid levels is a vision for the treatment of hyperuricemia, but the current comprehensive treatment of western medicine has many side effects and is relatively expensive

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0031] The granules for preventing and treating hyperuricemia can be prepared by adopting the following steps:

[0032] (1) Weigh 40 parts of equisetum, 40 parts of Imperata rhizome, 20 parts of cypress, 20 parts of golden grass, 20 parts of motherwort, 15 parts of iron-clad gold, 15 parts of golden flower grass, 15 parts of Smilax cocos, Add 15 parts of sumac, 15 parts of gourd tea, 15 parts of short ground tea, and 10 parts of licorice, add 12 times the total mass of raw materials in water, soak for 30 min, decoct for extraction for 1 h, extract once, filter, and combine the filtrates to obtain the extract a.

[0033] (2) Concentrate the extract A until the mass ratio of the liquid medicine is 0.5 g / mL, add ethanol to reach an alcohol content of 60%, settle for 12 hours, filter, recover ethanol, and concentrate, dry, and pulverize the filtrate to obtain water-extracted alcohol-precipitated Extract dry powder, save.

[0034] (3) Extract the dry powder obtained in step (2) b...

Embodiment 2

[0036] The tablet for preventing and treating hyperuricemia can be prepared by adopting the following steps:

[0037] (1) Weigh 35 parts of equisetum, 35 parts of Imperata rhizome, 18 parts of cypress, 18 parts of golden grass, 18 parts of motherwort, 12 parts of iron-clad gold, 12 parts of golden flower grass, 12 parts of Smilax cocos, 12 parts of sumac, 12 parts of gourd tea, 12 parts of low ground tea, 7 parts of licorice, Selaginella selaginella can be used instead of selaginella, add 14 times the total mass of raw materials in water, soak for 30 min, decoct for 1.5 h, and extract twice , filter, and combine the filtrates to obtain extract A.

[0038] (2) Concentrate the extract A until the mass ratio of the liquid is 1.0 g / mL, add ethanol until the alcohol content is 70%, and settle for 24 h. Filtrate, recover ethanol, concentrate, dry and pulverize the filtrate to obtain dry powder of water-extracted and alcohol-precipitated extract, which is stored.

[0039] (3) Extra...

Embodiment 3

[0041] The capsules for preventing and treating hyperuricemia can be prepared by adopting the following steps:

[0042] (1) Weigh 32 parts of equisetum, 32 parts of Imperata rhizome, 16 parts of cypress, 16 parts of golden grass, 16 parts of motherwort, 11 parts of iron-clad gold, 11 parts of golden flower grass, 11 parts of Smilax cocos, 11 parts of sumac, 11 parts of gourd tea, 11 parts of low ground tea, 6 parts of licorice, Selaginella selaginella can be used instead of selaginella, add 15 times the total mass of raw materials in water, soak for 30 min, decoct for 1.5 h, extract 3 times , filter, and combine the filtrates to obtain extract A.

[0043] (2) Concentrate the extract A until the mass ratio of the liquid is 1.0 g / mL, add ethanol until the alcohol content is 75%, settle for 36 hours, filter, recover ethanol, concentrate, dry and pulverize the filtrate to obtain the water extraction alcohol precipitation Extract dry powder, save.

[0044] (3) Extract the dry pow...

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PUM

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Abstract

The invention relates to a Zhuang medicine preparation for preventing and treating hyperuricemia. The Zhuang medicine preparation is prepared from the following raw materials in parts by weight: 10-20parts of all-grass of selaginella doederleinii hieron, 5-15 parts of radix berchemiae lineatae, 5-15 parts of Japanese claw fern herb, 20-40 parts of common scouring rush herb, 20-40 parts of lalanggrass rhizome, 10-20 parts of herba desmodii styracifolii, 10-20 parts of herba leonuri, 5-15 parts of rhizoma smilacis glabrae, 5-15 parts of lignum sappan, 5-15 parts of triquetrous tadehagi herb, 5-15 parts of herba ardisiae japonicae and 2-10 parts of radix glycyrrhizae. The Zhuang medicine preparation for preventing and treating hyperuricemia improves the current clinical treatment dilemma ofhyperuricemia, has the treatment effects of clearing heat, promoting diuresis, reducing blood uric acid, having a certain kidney protection effect and the like, can obviously improve the glomerular filtration rate and promote uric acid excretion, and is obvious in curative effect advantage and relatively low in price.

Description

technical field [0001] The invention relates to the technical field of Zhuang medicine traditional Chinese medicine preparations, in particular to a Zhuang medicine preparation for preventing and treating hyperuricemia and a preparation method thereof. Background technique [0002] The continuous progression of hyperuricemia is closely related to the occurrence and development of gout, acute cerebral infarction, vascular diseases, urinary system stones, renal dysfunction and other diseases, which directly or indirectly lead to gout and other diseases. Usually hyperuricemia is considered to be the cause of gout. According to statistics, about 5% to 12% of hyperuricemia can eventually develop into gout. At present, the comprehensive treatment methods of western medicine are mainly divided into inhibition of uric acid synthesis, promotion of uric acid excretion and other aspects. The clinical efficacy is limited, the medical side effects are many, the cost is high, and it is ea...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61K36/90A61P19/06
CPCA61K36/11A61K36/12A61K36/185A61K36/48A61K36/484A61K36/533A61K36/72A61K36/896A61K36/899A61K36/90A61K2236/331A61K2236/39A61K2236/53A61P19/06A61K2300/00
Inventor 滕红丽梅之南
Owner 滕红丽
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