Microfluidic chip and in-vitro detection device comprising microfluidic chip

Abstract

The invention relates to a microfluidic chip and an in-vitro detection device comprising the microfluidic chip. The microfluidic chip is provided with a sample adding cavity, a first microfluidic channel, a precipitation cavity, a second microfluidic channel, a first capillary flow channel, a third microfluidic channel and a quantitative detection cavity. The sample adding cavity, the precipitation cavity and the quantitative detection cavity are formed in the microfluidic chip, a to-be-detected sample can be added into the sample adding cavity through a sample adding hole, solid precipitate and liquid can be separated through centrifugal separation to obtain a to-be-detected sample solution containing a target substance, to-be-detected sample solutions in the sample adding cavity, the first microfluidic channel and the second microfluidic channel can be driven by a capillary force of the first capillary flow channel to flow, the liquid finally forms siphoning action and external centrifugal action to flow into the quantitative detection cavity to quantify the to-be-detected sample solution. The microfluidic chi has a relatively simple structure, is easy to manufacture and form andcan be widely popularized and used.

Description

technical field [0001] The invention relates to the technical field of in vitro diagnosis, in particular to a microfluidic chip and an in vitro detection device comprising the microfluidic chip. Background technique [0002] In Vitro Diagnosis (In Vitro Diagnosis, IVD) refers to the technology of taking samples (blood, body fluid, tissue, etc.) from the human body for detection and analysis to diagnose diseases. The detection process requires corresponding instruments and reagents, and these instruments and reagents An in vitro diagnostic system is formed. In vitro diagnostic systems are roughly divided into two types: one is represented by the testing center laboratory, which has the characteristics of system modularization and automation, and performs pipeline inspection on samples, so it also has high throughput, high efficiency, and high sensitivity. However, the entire system also has defects such as high cost, large volume, and the need for professional operation. It ...

AI Technical Summary

Problems solved by technology

However, the traditional microfluidic chips used for POCT generally have complex structures, so the price is relatively expensive, which limits its further application in the field of POCT.

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