An auxiliary positioning device for mouse brain injection

Abstract

The invention discloses an auxiliary positioning device for mouse brain injection, which comprises a constant temperature base plate, a vertical axis moving scale and a clamping assembly. The four corners of the lower surface of the constant temperature base plate are threaded with non-slip feet, and the inside of the constant temperature base plate is installed with A constant temperature heating assembly, a fixed component is fixed on the rear side of the upper surface of the constant temperature bottom plate, the vertical axis moving scale is installed on the left surface of the constant temperature bottom plate, and the upper end of the vertical axis moving scale is fixed with a vertical plate, the inside of the vertical axis A screw is installed in the middle position, and the top of the screw is welded with an adjustment handle. The outer wall of the screw is threaded with a ball slide, and the right side of the ball slide is equipped with a horizontal axis moving scale, and the clamping assembly is installed on the horizontal axis. Move the ruler below. The present invention greatly improves the accuracy of the entire positioning device by adopting a moving scale with a positioning accuracy of 0.01mm, thus solving the problem in the prior art that precise positioning cannot be performed due to the small hippocampus of mice.

Description

technical field [0001] The invention relates to the field of animal medical technology, in particular to an auxiliary positioning device for mouse brain injection. Background technique [0002] Memory is actually a form of connection between nerve cells. However, storing or discarding certain information is not based on conscious judgment, but is processed by the hippocampus in the human brain. The hippocampus acts as a switch during the memory process. When the neurons in the cerebral cortex receive various sensory or perceptual information, they will pass the information to the hippocampus. If the hippocampus responds, the neurons will begin to form a persistent network, but if there is no Through this recognized mode, the experience received by the brain will automatically disappear without a trace. A large number of experimental studies and clinical observations have shown that the hippocampus is a key part of learning and memory, especially the key brain area of ​​assoc...

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide an auxiliary positioning device for mouse brain injection, which solves the problem that the existing reports on rat hippocampal microinjection in the market are not uncommon, and most of them are cannula implantation methods. The use of mice is very common, but mice are not easy to perform microinjection because of their small hippocampus. When choosing different coordinates for different regions of the hippocampus for injection, there are still many deviations and it is difficult to accurately locate the problem.

Images