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Preparation technology of capsules having multiple treatment effects

A preparation process and capsule technology, which is applied in the field of preparation of multi-curative capsules, can solve the problems of low utilization rate of Chinese herbal medicines and low drug efficacy of capsules, and achieve the goal of reducing drug particle gaps, enhancing particle fluidity, and improving drug efficacy Effect

Inactive Publication Date: 2019-10-15
HEBEI AOXING GROUP PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The existing processing and production of Chinese patent medicines includes the following processes: batching--drying and sterilization--crushing--mixing--filling--packaging--storage. , the produced capsules are not highly effective

Method used

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  • Preparation technology of capsules having multiple treatment effects
  • Preparation technology of capsules having multiple treatment effects
  • Preparation technology of capsules having multiple treatment effects

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Example 1, a preparation process of multi-curative capsules, taking Zhongtongan Capsules provided by Aoxing Pharmaceutical Co., Ltd. as the experimental object, using the new technology and the original technology in Zhongtongan Capsules , Angelica dahurica, Gastrodia elata, Fangfeng, Notopterygium and Panax notoginseng superfine powder content were compared.

[0018] Bombworm:

[0019]

[0020] Summary: Judging from the extract, the superfine powder has improved.

[0021] White monkshood:

[0022]

[0023] Summary: Judging from the extract, the ultrafine powder is reduced.

[0024] Tiannanxing:

[0025]

[0026]

[0027] Summary: From the perspective of content, the content of superfine powder is higher than that of original coarse powder.

[0028] Angelica:

[0029]

[0030] Summary: Judging from the extract, the superfine powder is significantly higher than the coarse powder, and from the content, after the superfine powder, the content is slightl...

Embodiment 2

[0045] Example 2, a preparation process of a multi-curative capsule, taking the Zhongtongan Capsule provided by Aoxing Pharmaceutical Co., Ltd. as the experimental object.

[0046] Experiment 1. Effects on pain induced by 0.6% acetic acid in mice

[0047] Purpose of the test: To observe the effect of the new technology capsules produced by the new technology on Zhongtongan capsules on the pain induced by 0.6% acetic acid in mice, to evaluate its analgesic effect, and to compare the curative effect with the original technology.

[0048] experiment material:

[0049] Test substance: new technology of Zhongtongan Capsules, provided by Aoxing Pharmaceutical Co., Ltd.

[0050] Control drug: aspirin (0.30g / grain), Shanxi Taiyuan Pharmaceutical Co., Ltd.

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Abstract

The invention belongs to the technical field of capsules, and particularly relates to a preparation technology of capsules having multiple treatment effects. The capsules having multiple treatment effects are characterized by comprising stiff silkworm, giant typhonium rhizomes, prepared rhizoma arisaematis, radix angelicae, rhizoma gastrodiae, divaricate saposhnikovia roots, rhizoma et radix notopterygii and pseudo-ginseng. The preparation technology comprises the following steps of preferably selecting medicinal materials of the stiff silkworms, the giant typhonium rhizomes, the rhizoma arisaematis, the radix angelicae, the rhizoma gastrodiae, the divaricate saposhnikovia roots, the rhizoma et radix notopterygii and the pseudo-ginseng which are high in medicine property reserving degree,performing cleaning, performing drying in the shade for standby application, sequentially cutting the medicinal materials, crushing the cut medicinal materials, adding medicinal powder to a centrifuge, performing high-speed rotation, performing supercritical flow extraction on the medicinal materials to obtain essence substances by using carbon dioxide as a medium, and concentrating the essence substances of the medicinal materials. The medicine effects of the capsules having multiple treatment effects produced by the technology are remarkably improved, after the content of submicron powder isincreased, the granule gap of traditional Chinese medicine substances of the capsules is obviously reduced, the granule fluidity is reinforced, capsule shells having a same volume can accommodate more mass of medicine powder, and the medicine taking quantity of a patient can be reduced.

Description

technical field [0001] The invention relates to the technical field of capsule production, in particular to a preparation process of a multi-curative capsule. Background technique [0002] The existing processing and production of Chinese patent medicine includes the following processes: batching--drying and sterilization--crushing--mixing--filling--packaging--storage. The above-mentioned processing and production process of Chinese patent medicine is simple, and the utilization rate of Chinese medicinal materials is low , the produced capsules are not highly effective. Contents of the invention [0003] Based on the problems raised by the background technology, the present invention proposes a preparation process for multi-curative capsules. [0004] The preparation process of a multi-curative capsule proposed by the present invention, the multi-curative capsule includes Bombyx cypress, Radix Aconiti, Radix Araceae, Angelica dahurica, Gastrodia elata, Fangfeng, Notoptery...

Claims

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Application Information

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IPC IPC(8): A61K36/8988A61K9/48A61P29/00A61K35/64
CPCA61K9/1635A61K9/1652A61K35/64A61K36/232A61K36/237A61K36/238A61K36/258A61K36/888A61K36/8884A61K36/8988A61K2236/37A61P29/00A61K2300/00
Inventor 滑千里周桂荣赵学刚王乃浩牛建飞张琳宇岳晓华
Owner HEBEI AOXING GROUP PHARMA
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