Gastrointestinal endoscopy assisting water and preparation method thereof
A gastrointestinal and pure water technology, applied in gastroscope, rectal mirror, rectal electron microscope, etc., can solve problems such as preventing diagnosis, prolonging inspection time, and missing
Active Publication Date: 2019-10-11
奥纳斯(北京)医药科技有限公司
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Problems solved by technology
[0002] Medically, high-definition endoscopy is often used to check the lesions in the gastrointestinal tract. However, the mucus and foam in the gastrointestinal tract often affect the field of view of the endoscope, resulting in a low detection rate of small lesions and prolonged inspection time; and excessive contraction of the gastrointestinal tract is also Can prevent correct diagnosis and can allow small lesions such as cancerous sites of small size to be missed
In order to solve the above problems in the process of endoscopic examination, the prior art often uses emulsions containing L-menthol, which can inhibit the contraction of smooth muscles; Significantly lower light transmittance
Method used
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Embodiment 1
[0021]
Embodiment 2
[0023]
Embodiment 3
[0025]
[0026]
[0027] The preparation method of the auxiliary water for gastrointestinal endoscopy is:
[0028] Add diisopropanolamine, octadecyltrimethylammonium chloride and phosphatidylserine to purified water, stir for 5 min at 200 rpm, and let it stand. Add L-menthol, Span-80 and polyoxypropylene oxide ethylene glycerin Ether was added to the above solution and ultrasonicated to prepare auxiliary water. The ultrasonic conditions were: ultrasonic temperature 10°C, ultrasonic power 50w, ultrasonic time 5s, interval time 4s, cumulative ultrasonic time 30min.
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The invention provides a gastrointestinal endoscopy assisting water and a preparation method thereof. The assisting water consists of 1-3 parts of L-menthol, 0.5-1 part of a surfactant, 0.02-0.05 partof a defoaming agent and 90-96 parts of pure water. The provided gastrointestinal endoscopy assisting water can be used for rinsing the gastrointestinal tract and has excellent anti-foaming ability in a gastrointestinal environment, the defoaming speed is high, and the light transmittance rate is significantly better than that of existing emulsions.
Description
Technical field [0001] The invention belongs to the field of preparations for gastrointestinal endoscopy, and particularly relates to an auxiliary water for gastrointestinal endoscopy and a preparation method thereof. Background technique [0002] High-definition endoscopy is often used in medical treatment to examine the lesions in the gastrointestinal tract. However, mucus and foam in the gastrointestinal tract often affect the field of vision of the endoscopy, resulting in a low detection rate of small lesions and a prolonged examination time; and then excessive contraction of the gastrointestinal tract also It will prevent a correct diagnosis and cause minor damage such as small cancerous sites to be missed. In order to solve the above problems in the process of endoscopy, the prior art often uses emulsions containing L-menthol, which can inhibit smooth muscle contraction; however, it cannot replace the water used in the gastrointestinal tract and is used in artificial gastri...
Claims
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IPC IPC(8): A61K9/08A61K47/10A61K47/46A61K47/22A61B1/273A61B1/31
CPCA61B1/2736A61B1/31A61K9/08A61K47/10A61K47/22A61K47/46
Inventor 李苏
Owner 奥纳斯(北京)医药科技有限公司
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