Application of centella asiatica extract in preparing traditional Chinese medicine product for nourishing ovary

A centella asiatica extract and extract technology, which is applied in the field of preparing ovary-nourishing traditional Chinese medicine products, centella asiatica extract, to achieve significant proliferation, increase the secretion level of estrogen and progesterone, and expand the application range

Inactive Publication Date: 2019-09-17
INST OF BOTANY JIANGSU PROVINCE & CHINESE ACADEMY OF SCI +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no report on the application of centella asiatica extract to improve the activity of ovarian granulosa cells and nourish the ovaries

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Embodiment 1: preparation centella asiatica extract

[0014] Take centella asiatica medicinal material, crush and sieve, add 8 times of 70% ethanol to soak, extract under heat reflux for 2-4 hours, and concentrate the extract under reduced pressure to obtain a solid dry powder that is centella asiatica alcohol extract.

Embodiment 2

[0015] Embodiment 2: preparation centella asiatica extract

[0016] Take centella asiatica medicinal material, crush and sieve, add 9 times of 80% ethanol to soak, extract under heat reflux for 2-4 hours, and concentrate the extract under reduced pressure to obtain a solid dry powder that is centella asiatica alcohol extract.

Embodiment 3

[0017] Embodiment 3: preparation centella asiatica extract

[0018] Take centella asiatica medicinal material, crush and sieve, add 10 times of 90% ethanol to soak, extract under heat reflux for 2-4 hours, and concentrate the extract under reduced pressure to obtain a solid dry powder that is centella asiatica alcohol extract.

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PUM

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Abstract

The invention discloses application of a centella asiatica extract in preparing a traditional Chinese medicine product for nourishing the ovary. According to the pathogenesis of ovarian dysfunction and ovarian granulosa cell insufficiency, traditional Chinese medicine resources are fully utilized, and on the basis of preparing the centella asiatica extract, the new application of the centella asiatica extract in treating ovary dysfunction and improving the activity of ovarian granulosa cells is developed through a pharmacological experiment. The extract can be added into traditional Chinese medicine products of different dosage forms, the ovary can be regulated to achieve the effect of nourishing the ovary by promoting proliferation of the ovarian granulosa cells and improving the secretion level of estrogen and progesterone, and the centella asiatica extract is clinically used for treating the ovary dysfunction, and has the advantages that the therapeutic effect is good, effective components are clear, the side effect is small, and the use is convenient.

Description

technical field [0001] The invention belongs to the medical field of traditional Chinese medicine, and in particular relates to a new application of centella asiatica extract capable of improving the activity of ovarian granulosa cells in preparing traditional Chinese medicine products for nourishing ovaries. Background technique [0002] The physiological functions of the ovary include ovulation and endocrine functions, which are of great significance to women's reproductive function, physical and mental health and quality of life. Ovarian dysfunction can lead to ovulation dysfunction, abnormal corpus luteum function and endocrine disorders, etc., which can cause a variety of gynecological diseases, such as uterine dysplasia, infertility, premature ovarian failure, perimenopausal syndrome, etc., and can affect other organs throughout the body. The physiological function of the organ. [0003] The ovary is an important reproductive organ in the reproductive system of female...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/23A61P15/00A61P15/08
CPCA61K36/23A61K2236/333A61P15/00A61P15/08
Inventor 宋萍萍毛艳韦敏姜晓雁吕晔钱怡云颜露
Owner INST OF BOTANY JIANGSU PROVINCE & CHINESE ACADEMY OF SCI
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