A kind of pharmaceutical composition for treating stable stage of bronchiectasis and its preparation method and application

A technology of bronchiectasis and composition, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., to achieve good safety, relieve clinical symptoms and signs, and slow down the effect of disease progression

Active Publication Date: 2021-09-03
TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are no Codonopsis pilosula, Poria cocos, Pinellia chinensis, tangerine peel, bran-fried Atractylodes macrocephala, amomum, woody fragrance, raw licorice, yam, coix seed, wine skullcap, sunburned astragalus, schisandra, lily, Moutan bark, and rehmannia root for treatment. A report on the stable phase of bronchiectasis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1, the preparation of the pharmaceutical composition of the present invention

[0024] Prescription: Codonopsis 30g, Poria 15g, Pinellia 15g, dried tangerine peel 15g, Bran fried Atractylodes 15g, Amomum 15g, Muxiang 10g, Raw licorice 10g, Chinese yam 30g, Coix seed 30g, wine scutellaria 10g, roasted astragalus 30g, Schisandra 10g , Lily 20g, Cortex Moutan 15g, Rehmannia glutinosa 15g.

[0025] Preparation method: according to the above prescription ratio, first put Codonopsis pilosula, Poria, Pinellia japonica, dried tangerine peel, bran fried Atractylodes, raw licorice, Chinese yam, Coix seed, wine Scutellaria baicalensis, Zhi Astragalus, Schisandra chinensis, lily, Cortex Moutan, and Rehmannia glutinosa. In a casserole, add 2500ml of water and soak for 0.5 hours. After boiling for 1 to 1.5 hours with strong fire (high fire), add Amomum, wood incense, and continue to cook for 10 to 15 minutes with slow fire. Pour the boiled medicinal liquid into a clean co...

Embodiment 2

[0026] Embodiment 2, the preparation of the pharmaceutical composition of the present invention

[0027] Prescription: Codonopsis 20g, Poria 10g, Pinellia 10g, dried tangerine peel 10g, Bran fried Atractylodes 10g, Amomum 10g, Muxiang 5g, Raw licorice 5g, Chinese yam 20g, Coix seed 20g, Wine Scutellaria 5g, Baked Astragalus 20g, Schisandra 5g , Lily 10g, Cortex Moutan 10g, Rehmannia glutinosa 10g.

[0028] Preparation method: same as Example 1.

Embodiment 3

[0029] Embodiment 3, the preparation of the pharmaceutical composition of the present invention

[0030] Prescription: Codonopsis 40g, Poria 20g, Pinellia 20g, Chenpi 20g, Bran fried Atractylodes 20g, Amomum 20g, Muxiang 15g, Raw licorice 15g, Chinese yam 40g, Coix seed 40g, Wine Scutellaria 15g, Baked Astragalus 40g, Schisandra 15g , Lily 30g, Cortex Moutan 20g, Rehmannia glutinosa 20g.

[0031] Preparation method: same as Example 1.

[0032] The beneficial effects of the present invention will be described below through test examples.

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PUM

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Abstract

The invention provides a pharmaceutical composition for treating bronchiectasis in the stable phase, which is a preparation prepared from raw materials with the following weight proportions: Codonopsis 20-40 parts, Poria cocos 10-20 parts, French half 10-20 parts of summer, 10-20 parts of tangerine peel, 10-20 parts of bran-fried Atractylodes macrocephala, 10-20 parts of amomum, 5-15 parts of woody fragrance, 5-15 parts of raw licorice, 20-40 parts of yam, 20 parts of coix seed ~40 parts, 5~15 parts of wine skullcap, 20~40 parts of sunburned astragalus, 5~15 parts of Schisandra chinensis, 10~30 parts of lily, 10~20 parts of Moutan cortex, 10~20 parts of rehmannia glutinosa. The pharmaceutical composition provided by the invention has a precise formula, can alleviate the clinical symptoms and signs of patients with stable bronchiectasis, and slow down the progress of the disease. Moreover, the composition of the invention has good safety, no toxic and side effects, and is easy to use. It is suitable for clinical treatment of stable bronchiectasis. A new drug option is offered.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a pharmaceutical composition for treating bronchiectasis in stable phase and a preparation method and application thereof. Background technique [0002] Bronchiectasis is the pathological and persistent expansion of the bronchial tree caused by various reasons, resulting in recurrent purulent infection and chronic airway inflammation. The clinical manifestations are persistent or recurrent cough, expectoration and other symptoms. The stable phase (or remission phase) of bronchiectasis refers to the stable symptoms such as cough and expectoration, and is not in the clinical exacerbation phase. In recent years, the prevalence of this disease has gradually increased, and it is a common disease in the respiratory department. It often requires antibiotic treatment due to acute exacerbation of infection; even in the stable stage (or remission stage), the patient still has p...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9064A61P11/00
Inventor 黄青松张传涛吴建英肖玮王成黄群
Owner TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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