Method for screening acne-removing compound containing coptis chinensis, cortex phellodendri, radix scutellariae and rheum officinale

Abstract

The invention discloses a method for screening an acne-removing compound containing coptis chinensis, cortex phellodendri, radix scutellariae and rheum officinale. Based on a traditional acne-removingformula of rheum officinale, radix scutellariae and cortex phellodendri, traditional Chinese herbal medicinal aqueous extracts of coptis chinensis, cortex phellodendri, radix scutellariae and rheum officinale are selected as acne-removing effective ingredients, a four-factor three-level orthogonal testing method is adopted for compounding, the DPPH cleaning capability, hyaluronidase inhibitability, 5 alpha-reductase activity inhibitability and staphylococcus aureus inhibitability of each compound are analyzed by a modern testing method, and scientific analysis and comparison are performed from the four aspects to determine an optimized compounding proportion, and a scientific accordance is provided to the influence of dosage of four traditional Chinese herbal medicinal materials on the compound acne-removing effect. The coptis chinensis, cortex phellodendri, radix scutellariae and rheum officinale are natural materials, accord with the concept of safe skin protection of modern people,and have more advantages in application in comparison with acne-removing medicines and acne-removing cosmetics on the market. The method is modern application of an ancient formula and provides relatively good technical support to researches and development of compound acne-removing products containing coptis chinensis, cortex phellodendri, radix scutellariae and rheum officinale.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine combinations, and in particular relates to a screening method of Sihuang Acne Removing Compound. Background technique [0002] Acne has become one of the biggest problems for young people. Traditional Chinese medicine believes that the causes of acne can be summarized as lung heat, blood heat, damp heat, wind heat, external attack of wind evil, yin deficiency and blood stasis, imbalance of yin and yang, disharmony of qi and blood, Accumulated heat in the stomach and intestines, Chong Ren disorder, etc., mostly belong to fever. Among the ancient anti-acne prescriptions, Sanhuang Fu, Sanhuang Powder, and Sanhuang Cream are the most widely used. The three yellows are Coptis, Scutellaria, and Phellodendron, or Coptis, Phellodendron, and Rhubarb. Coptis chinensis, Phellodendron Phellodendron, and Scutellaria baicalensis belong to heat-clearing medicines, and rhubarb belongs to pur...

AI Technical Summary

Problems solved by technology

[0004] From the analysis of the mechanism of acne, it can be found that traditional Chinese medicinal materials need to play a certain role in each stage of acne in order to achieve a better anti-acne effect. There is no specific research on the effect of the anti-acne effect of the compound formula, so people do not have a clear understanding of the anti-acne effect of the traditional Chinese medicine compound used

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