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Method of cough granule quality control

A quality control method, particle technology, used in measuring devices, instruments, scientific instruments, etc.

Inactive Publication Date: 2019-02-15
广西中医药大学附属瑞康医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no literature report on its quality control. In order to better control the quality of Zhideke Granules, it is necessary to establish quality control methods such as identification and content determination, so as to effectively control the quality of the drug and ensure its clinical efficacy.

Method used

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  • Method of cough granule quality control
  • Method of cough granule quality control
  • Method of cough granule quality control

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 1

[0071] The prescription of the Zhideke granules of the present invention is:

[0072] Platycodon grandiflorum 85g Loquat leaves 85g Dragon's leaves 85g White front 85g Shegan 85g Nepeta 65g Green sky sunflower 65g Scutellaria 65g

[0073] Mint 65g Bupleurum 95g

[0074] The preparation method of Zhideke granules of the present invention is:

[0075] The above ten medicinal materials, nepeta, peppermint, add 6 times the amount of water to extract the volatile oil for 2 hours, the distilled aqueous solution is stored in another device, and the remaining eight flavors are added 10 times, 8 times, and 8 times with water in turn, decocted three times, 1.5 times each After hours, filter the combined medicinal solution, combine with the above aqueous solution, and concentrate to an extract with a relative density of 1.10 (60°C), add ethanol to make the alcohol content reach 70%, stir well, let stand for more than 24 hours, and filter the supernatant , Recycle the ethanol, concentrate it to ...

specific Embodiment 2

[0097] The prescription of the Zhideke granules of the present invention is:

[0098] Platycodon grandiflorum 85g Loquat leaves 85g Dragon's leaves 85g White front 85g Shegan 85g Nepeta 65g Green sky sunflower 65g Scutellaria 65g

[0099] Mint 65g Bupleurum 95g

[0100] The preparation method of Zhideke granules of the present invention is:

[0101] The above ten medicinal materials, nepeta, peppermint, add 6 times the amount of water to extract the volatile oil for 2 hours, the distilled aqueous solution is stored in another device, and the remaining eight flavors are added 10 times, 8 times, and 8 times with water in turn, decocted three times, 1.5 times each After hours, filter the combined medicinal solution, combine with the above aqueous solution, and concentrate to an extract with a relative density of 1.10 (60°C), add ethanol to make the alcohol content reach 70%, stir well, let stand for more than 24 hours, and filter the supernatant , Recycle the ethanol, concentrate it to ...

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PUM

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Abstract

The invention provides a method of cough granule quality control. The loquat leaf, Cynanchum glaucescens, Belamcanda chinensis, Scutellaria baicalensis Georgi and Bupleurum chinensis in cough granulesare identified by TLC while Baicalin and Irisflorentin are simultaneously determined by high performance liquid chromatography. This quality control method can solve the problem of identifying multiple flavors and separating complex components of prescribed traditional Chinese medicine, having good specificity and reproducibility. The quality control method of the invention can control product quality effectively, thereby ensuring the effectiveness of its clinical use.

Description

【Technical Field】 [0001] The invention relates to a quality control method for Zhideke granules, and belongs to the field of quality inspection of traditional Chinese medicine preparations. 【Background technique】 [0002] Cough is a common symptom of the respiratory tract. Traditional Chinese medicine believes that cough is caused by unclear lung qi, loss of Xuan Su, and upward noise. The main symptoms are cough and expectoration. More common in acute bronchitis, chronic bronchitis. Zhideke Granules have the effects of clearing away heat, detoxifying, relieving cough and reducing phlegm, and are effective in treating colds and coughs, headaches, nose spray, acute and chronic bronchitis, pneumonia cough, laryngitis, etc. However, there is no literature report on its quality control. In order to better control the quality of Zhideke granules, it is necessary to establish quality control methods such as identification and content determination to effectively control the quality of...

Claims

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Application Information

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IPC IPC(8): G01N30/02G01N30/06G01N30/90
CPCG01N30/02G01N30/06G01N30/90
Inventor 黄敏黄国东韦瑀龙谢广源黄燕琼
Owner 广西中医药大学附属瑞康医院
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