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A kind of triglyceride quality control solution and preparation method thereof

A technology of triglycerides and preparation methods, which is applied in the preparation of test samples, analysis by making materials undergo chemical reactions, and material analysis by observing the impact on chemical indicators, etc., can solve the problem of high cost and achieve deviation The effect of low degree of accuracy, reduced interference, and high degree of coincidence

Active Publication Date: 2021-06-29
QINGDAO HIGHTOP BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] The object of the present invention is to provide a new triglyceride quality control solution and its preparation method. The quality control product is prepared with ethylene glycol and TritonX-100, which overcomes the high cost of the triglyceride quality control product in the prior art and its dissolution. The problem is that it can not only completely dissolve triglycerides, but also form a relatively uniform and stable state, which is more conducive to laboratory product testing and overcomes the current problem of purchasing quality control products for serum triglycerides

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  • A kind of triglyceride quality control solution and preparation method thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0036] A triglyceride quality control solution, including triglyceride serum quality control product mother solution and diluent;

[0037] The triglyceride serum quality control product mother liquor is a triglyceride solution containing triolein and a surfactant, and its main components are: triolein 10% (mass ratio), TritonX-100 0.5% (volume proportion), ethylene glycol 70% (volume proportion), fetal bovine serum 14.5% (volume proportion), BSA 5% (mass proportion);

[0038] The diluent is a solution containing a certain surfactant, and its main components are: ethylene glycol 60% (volume ratio), fetal bovine serum 36% (volume ratio), BSA 5% (mass ratio).

[0039] The preparation method of the above-mentioned a kind of triglyceride quality control liquid, comprises the preparation method of mother liquor of triglyceride serum quality control product and the preparation method of diluent;

[0040] Described triglyceride serum quality control product mother solution preparatio...

Embodiment 2

[0048] A triglyceride quality control solution, including a triglyceride serum quality control product mother solution and a diluent;

[0049] The triglyceride serum quality control product mother liquor is a triglyceride solution containing triolein and a surfactant, and its main components are: triolein 9.5% (mass ratio), TritonX-100 1% (volume proportion), ethylene glycol 75% (volume proportion), fetal bovine serum 10% (volume proportion), BSA 4.5% (mass proportion);

[0050] The diluent is a solution containing a certain surfactant, and its main components are: ethylene glycol 60.5% (volume ratio), fetal bovine serum 35% (volume ratio), BSA 4.5% (mass ratio).

[0051] The preparation method of the above-mentioned a kind of triglyceride quality control liquid, comprises the preparation method of mother liquor of triglyceride serum quality control product and the preparation method of diluent;

[0052] Described triglyceride serum quality control product mother solution pre...

Embodiment 3

[0060] A triglyceride quality control solution, including triglyceride serum quality control product mother solution and diluent;

[0061] The triglyceride serum quality control product mother liquor is a triglyceride solution containing triolein and a surfactant, and its main components are: triolein 9.5% (mass ratio), TritonX-100 0.8% (volume ratio), ethylene glycol 72.5% (volume ratio), fetal bovine serum 12.5% ​​(volume ratio), BSA 4% (mass ratio);

[0062] The diluent is a solution containing a certain surfactant, and its main components are: ethylene glycol 61% (volume ratio), fetal bovine serum 34% (volume ratio), BSA 4% (mass ratio).

[0063] The preparation method of the above-mentioned a kind of triglyceride quality control liquid, comprises the preparation method of mother liquor of triglyceride serum quality control product and the preparation method of diluent;

[0064] Described triglyceride serum quality control product mother solution preparation method, compr...

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Abstract

The invention belongs to the field of in vitro diagnostic reagents, and discloses a triglyceride quality control solution and a preparation method thereof, a triglyceride quality control solution, including triglyceride serum quality control product mother solution and diluent; triglyceride serum quality control solution The control product mother liquor is a triglyceride solution containing triolein and surfactant, and its main components are: triolein, TritonX-100, ethylene glycol, fetal bovine serum, BSA; Surfactant solution, its main components are: ethylene glycol, fetal bovine serum, BSA, the present invention can not only completely dissolve triglyceride, and can form a relatively uniform and stable state, which is more conducive to laboratory product detection, overcomes the The current serum triglyceride quality control purchase problem.

Description

technical field [0001] The invention belongs to the field of in vitro diagnostic reagents, in particular to a triglyceride quality control solution and a preparation method thereof. Background technique [0002] Triglyceride (Triglyceride, TG), also known as neutral fat, is composed of three molecules of fatty acid and one molecule of glyceride, and is the main source of energy in the body. The level of triglycerides is not only positively correlated with total cholesterol (TC), body mass index (BMI) and blood glucose (GLU), but also closely related to obesity. The detection of triglycerides in human blood is very important, because its high concentration (normal range 40-160mg / dL for men and 35-135mg / dL for women) can lead to hyperlipidemia, which is the main cause of coronary heart disease. One of the manifestations, timely detection is helpful for the diagnosis and treatment of various endocrine disorders related to lipid metabolism in diabetes, nephropathy, liver obstru...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N1/38G01N21/78
CPCG01N1/38G01N21/78
Inventor 杨帆纵帅徐丽徐庆君崔欣宋金玲顾晓云刘美雪
Owner QINGDAO HIGHTOP BIOTECH
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