Absorbable and knotting-free surgical suture capable of continuously resisting infection and used for thoracic surgery department

A surgical suture and anti-infection technology, which is applied in the field of medical supplies, can solve the problems that non-biodegradable sutures cannot be absorbed by the body, prolong the operation time and anesthesia time, and increase the risk factor of patients, so that it is not easy to slip off and slow release Good performance and strong biocompatibility

Inactive Publication Date: 2018-11-23
王传强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Non-biodegradable sutures cannot be absorbed by the body, and there are different degrees of tissue reactions. Sutures on the epidermis, especially local skin, will leave scars; and the sutures are generally a whole line, and it takes a lot of time to thread the needle before the operation. When doing continuous sutures, several knots are often tied after the first stitch to prevent the suture from slipping.
However, due to the limited space at the wound site, this method of operation will not only add some extra complicated steps, but also prolong the operation time and anesthesia time accordingly, which will increase the risk factor of patients

Method used

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  • Absorbable and knotting-free surgical suture capable of continuously resisting infection and used for thoracic surgery department
  • Absorbable and knotting-free surgical suture capable of continuously resisting infection and used for thoracic surgery department
  • Absorbable and knotting-free surgical suture capable of continuously resisting infection and used for thoracic surgery department

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Such as figure 1 , figure 2 As shown, a kind of absorbable knot-free surgical suture with continuous anti-infection for thoracic surgery is composed of PPDO fiber core 1 located inside, composite drug-loaded layer 2 located in the middle layer and collagen layer 4 located in the outermost layer, A plurality of conical bosses 3 are evenly distributed on the composite drug-loaded layer 2, and the conical bosses 3 are integrally formed with the composite drug-loaded layer 2. The conical bosses 3 are composed of inclined surfaces 5 and mesa 6, and the conical bosses The slope 5 of 3 faces the needle-threading direction of the suture 7 , the mesa 6 faces the direction opposite to the needle-threading direction of the suture 7 , and the mesa 7 is perpendicular to the surface of the composite drug-loaded layer 2 .

[0022] The composite drug-loaded layer 2 is made of konjac glucomannan, quaternary ammonium chitosan, hyaluronic acid, and genipin, and the composite drug-loaded...

Embodiment 2

[0028] Such as image 3 , Figure 4 As shown, a kind of absorbable knot-free surgical suture with continuous anti-infection for thoracic surgery is composed of PPDO fiber core 1 located inside, composite drug-loaded layer 2 located in the middle layer and collagen layer 4 located in the outermost layer, A plurality of conical bosses 3 are evenly distributed on the composite drug-loaded layer 2, and the conical bosses 3 are integrally formed with the composite drug-loaded layer 2. The conical bosses 3 are composed of inclined surfaces 5 and mesa 6, and the conical bosses The slope 5 of 3 faces the needle-threading direction of the suture 7, the mesa 6 faces the direction opposite to the needle-threading direction of the suture 7, and the angle between the mesa 7 and the surface of the composite drug-loaded layer 2 is an acute angle greater than 30°.

[0029] The composite drug-loaded layer 2 is made of konjac glucomannan, quaternary ammonium chitosan, hyaluronic acid, and geni...

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Abstract

The invention provides an absorbable and knotting-free surgical suture capable of continuously resisting infection and used for thoracic surgery department. The absorbable and knotting-free surgical suture is composed of a PPDO (polydioxanone) fiber core located at the inner part, a compound drug-loading layer located in a middle layer and a collagen layer located on the outermost layer, wherein aplurality of tapered lug bosses are uniformly distributed on the compound drug-loading layer; the tapered lug bosses and the compound drug-loading layer are integrally molded; each tapered lug boss is composed of an inclined plane and a tabletop; the compound drug-loading layer is prepared from konjac glucomannan, quatemary ammonium salt chitosan, hyaluronic acid and genipin. The surgical sutureprepared by the invention does not need to be knotted in a surgery suturing process, can smoothly pass through muscle, does not easily slip off and has good biocompatibility; the absorbable and knotting-free surgical suture has a slow-release and antibacterial effect; after the absorbable and knotting-free surgical suture is degraded in a body, a product is discharged out of the body through metabolism, so that the absorbable and knotting-free surgical suture has no dangers and no toxic side effect.

Description

technical field [0001] The invention belongs to the technical field of medical supplies, and in particular relates to an absorbable knot-free surgical suture with continuous anti-infection for thoracic surgery. Background technique [0002] Thoracic surgery is a medical specialty that specializes in the study of thoracic organs, mainly referring to the diagnosis and treatment of esophageal, lung, and mediastinal lesions. The field of breast surgery is also included in this specialty, and pulmonary surgery and esophageal surgery are the main ones. Thoracic surgical conditions often require surgery. [0003] Surgical suture is a kind of sterile thread used for wound suture, tissue ligation and fixation, and it is one of the important materials in thoracic surgery. Non-biodegradable sutures cannot be absorbed by the body, and there are different degrees of tissue reactions. Sutures on the epidermis, especially local skin, will leave scars; and the sutures are generally a whole...

Claims

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Application Information

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IPC IPC(8): A61L17/10A61L17/00A61L17/14A61B17/06
CPCA61B17/06166A61B2017/06176A61L17/005A61L17/10A61L17/145A61L2300/216A61L2300/232A61L2300/236A61L2300/404A61L2300/45A61L2300/606
Inventor 王传强
Owner 王传强
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