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Medical use of amentoflavone in treatment of chicken necrotic enteritis

A technology of biflavonoids of Suicha spica and chicken necrotic enteritis, which is applied in the field of medicine to achieve the effect of reducing the degree of pathological changes and good therapeutic effect

Active Publication Date: 2018-11-23
JILIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, a large number of literatures have reported on the pharmacological activity of afenoflavones, but up to now, there is no relevant research on the use of afenoflavones in the treatment of chicken necrotic enteritis caused by Clostridium perfringens at home and abroad.

Method used

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  • Medical use of amentoflavone in treatment of chicken necrotic enteritis
  • Medical use of amentoflavone in treatment of chicken necrotic enteritis
  • Medical use of amentoflavone in treatment of chicken necrotic enteritis

Examples

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Embodiment 1

[0029] The application of the biflavone in the preparation of the medicine for treating chicken necrotic enteritis is to make the biflavone into any pharmaceutically acceptable dosage form with the activity of the biflavone in the chicken.

Embodiment 2

[0031] The treatment of necrotic enteritis in chickens described by abiflavone refers to necrotic enteritis caused by bacteria.

Embodiment 3

[0033] The treatment of necrotic enteritis in chickens described by the biflavone refers to necrotic enteritis caused by Clostridium perfringens.

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Abstract

The invention relates to the medical use of amentoflavone in treatment of chicken necrotic enteritis. The clostridium perfringen sliding motion inhibition test, the biofilm formation inhibition test,the chicken necrotic enteritis model treatment test, and the histopathological section observation and intestinal flora analysis test confirm that the amentoflavone has protective effects against chicken necrotic enteritis caused by clostridium perfringen infection. Due to the abuse of traditional antibiotics and the continuous enhancement of bacterial drug resistance, the amentoflavone has the characteristics of high cure rate, no drug resistance and drug residues. Therefore, the amentoflavone is used for treating chicken necrotic enteritis, which can increase the selectivity of use of drugs,and has an important significance for the development of new drugs.

Description

technical field [0001] The invention discloses the medical use of the biflavonoids of spiky chinensis in treating chicken necrotic enteritis, relates to the application of the biflavones of spiky spiky in the preparation of medicines for treating chicken necrotic enteritis, and belongs to the technical field of medicine. Background technique [0002] Clostridium perfringens is an anaerobic Gram-positive bacillus, which widely exists in soil, water, food, human and animal feces, livestock feed and animal intestines in nature, and is the normal intestinal flora of humans and animals , an opportunistic pathogen. At present, according to the different exotoxins it secretes, it is divided into 5 serotypes, A-E, and poultry are mainly infected with type A and type C Clostridium perfringens, especially type A. After Clostridium perfringens infects poultry, it mainly causes necrotic enteritis, and its symptoms are manifested as listlessness, loose feathers, loss of appetite or wast...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/352A61P1/00A61P31/04
CPCA61K31/352A61P1/00A61P31/04
Inventor 邓旭明刘水王建锋张建吕强华李淑芳
Owner JILIN UNIV
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