Microcirculation resistance index calculation method based on radiography image and hydrodynamics model

Abstract

The invention discloses a microcirculation resistance index calculation method based on a radiography image and a hydrodynamics model. The method comprises steps of selecting coronary artery images oftwo positions to carry out segmentation so as to obtain a coronary artery center line and a diameter; generating a coronary artery three-dimensional mode; acquiring blood conduction time Tmn and thespeed; establishing a blood vessel three-dimensional network; based on the coronary artery center line and the diameter of the X-ray reconstruction, generating an axially symmetrical two-dimensional plane mode; then, establishing two-dimensional axially symmetrical grids; measuring aorta mean blood pressure Pa; based on the obtained blood flow speed and the generated blood vessel three-dimensionalnetwork, solving fundamental formula of incompressible flows, and calculating the pressure drop deltaPi of each point from the entrance to the downstream along with the blood vessel center line, wherein the coronary artery far-end artery pressure Pd=Pa-deltaPi; and calculating the microcirculation resistance index IMR=Pd*Tmn. According to the invention, there is no need to carry out measurement through pressure guide wires, so operation is simple; operation difficulty and risk are greatly reduced; and the method can be clinically promoted and applied in large scale.

Description

technical field [0001] The invention relates to the field of coronary imaging evaluation, in particular to a method for calculating microcirculation resistance index based on contrast images and fluid dynamics models. Background technique [0002] Coronary heart disease is a serious heart disease. Percutaneous coronary intervention (PCI) has become an important means of treatment for coronary heart disease. Years of research have shown that PCI can treat coronary heart disease, especially acute coronary syndrome (acute coronary syndrome, ACS). However, existing studies have shown that even with coronary intervention or coronary artery bypass grafting, 25% of patients still fail to achieve myocardial reperfusion at the tissue level after successful epicardial vessel reconstruction. The main reason is the dysfunction of coronary microcirculation. Impaired coronary microcirculation function is an independent risk factor determining the prognosis of acute myocardial infarction,...

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Problems solved by technology

[0005] However, the above-mentioned pressure guide wire needs to intervene in the end of the blood vessel to measure IMR, which increases the difficulty and risk of the operation. At the same time, the expensive price of the pressure guide wire also limits its large-scale application.

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