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Purification and extraction technology of blood glucose lowering traditional Chinese medicines

A technology for lowering blood sugar and traditional Chinese medicine, applied in the field of biomedicine

Inactive Publication Date: 2018-08-17
JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At home and abroad, there are no relevant literature or patent reports on the extraction and purification technology of hypoglycemic drugs from succulent grass and prickly beans

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1: Extraction and Purification of Hypoglycemic Drugs in Fructus Carinae, Prickly Prunus Beans

[0027](1) Take 60 parts by weight of succulent grass and 25 parts by weight of prickly beans, grind them into coarse powder, extract 3 times with water as solvent, soak and extract at room temperature for 4 hours each time, the amount of water used is the total weight of succulents and pruritic beans 12 times of that, filter, and combine the filtrates to obtain extract A; the dregs after extraction are then extracted twice with water as a solvent, each heating and reflux extracting for 1.5 hours, and the water consumption is 10 times of the total weight of the succulent grass and the pruritic bean , filtered, and combined filtrates to obtain extract B; the extracted medicinal residues were then heated and refluxed with 70% ethanol as a solvent to extract for 0.5 hours, filtered, and combined filtrates were obtained to obtain extract E;

[0028] (2) Concentrate the ext...

Embodiment 2

[0036] Example 2: Extraction and Purification of Hypoglycemic Drugs in Flesh Fruit Grass and Prickly Peanuts

[0037] (1) Take 80 parts by weight of succulent grass and 100 parts by weight of prickly beans, grind them into coarse powder, extract 3 times with water as solvent, soak and extract at room temperature for 4 hours each time, the amount of water is the total weight of succulents and pruritic beans 12 times of that, filter, and combine the filtrates to obtain extract A; the dregs after extraction are then extracted twice with water as a solvent, each heating and reflux extracting for 1.5 hours, and the water consumption is 10 times of the total weight of the succulent grass and the pruritic bean , filtered, and combined filtrates to obtain extract B; the extracted medicinal residues were then heated and refluxed with 70% ethanol as a solvent to extract for 0.5 hours, filtered, and combined filtrates were obtained to obtain extract E;

[0038] (2) Concentrate the extrac...

Embodiment 3

[0046] Example 3: Extraction and Purification of Hypoglycemic Drugs in Flesh Fruit Grass and Prickly Peanuts

[0047] (1) Take 15 parts by weight of succulent grass and 50 parts by weight of prickly beans, grind them into coarse powder, extract 3 times with water as solvent, soak and extract at room temperature for 4 hours each time, the amount of water used is the total weight of succulents and pruritic beans 12 times of that, filter, and combine the filtrates to obtain extract A; the dregs after extraction are then extracted twice with water as a solvent, each heating and reflux extracting for 1.5 hours, and the water consumption is 10 times of the total weight of the succulent grass and the pruritic bean , filtered, and combined filtrates to obtain extract B; the extracted medicinal residues were then heated and refluxed with 70% ethanol as a solvent to extract for 0.5 hours, filtered, and combined filtrates were obtained to obtain extract E;

[0048] (2) Concentrate the ex...

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Abstract

The technical scheme of the invention discloses a purification and extraction technology of blood glucose lowering traditional Chinese medicines. A blood glucose lowering drug is prepared by the following method of taking lancea tibetica and mucuna pruriens as raw materials, performing extraction, separation and purification to obtain the blood glucose lowering drug prepared from mucuna pruriens ketone A, mucuna pruriens ketone B, phillyrin and catalpol.

Description

technical field [0001] The invention belongs to the field of biomedicine, and relates to an extraction and purification technology of a blood sugar-lowering traditional Chinese medicine, in particular to an extraction and purification technology of a blood sugar-lowering drug in Chinese medicines such as succulents and pruritic bean. Background technique [0002] Traditional Chinese medicine comes from plants, animals, and minerals, and is an important part of medicine. As early as the early Shang Dynasty, people extracted and prepared medicines from traditional Chinese medicines for disease prevention and treatment, such as Chinese medicine decoction for oral administration or external use; Ming Dynasty "Compendium of Materia Medica" recorded in detail the process of preparing and purifying camphor by sublimation method; "White Ape" describes the method of extracting and separating crystalline aconitine from fresh Aconitum aconitum; "Introduction to Medicine" records the pr...

Claims

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Application Information

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IPC IPC(8): A61K36/80A61P3/10
CPCA61K36/80A61K36/48A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55A61P3/10A61K2300/00
Inventor 李静超
Owner JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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