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Combined bioartificial liver supporting system

A liver support system, bioartificial technology, applied in dialysis systems, biochemical equipment and methods, specific-purpose bioreactors/fermenters, etc. Increased difficulty and other issues

Active Publication Date: 2018-06-29
ZHUJIANG HOSPITAL SOUTHERN MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, the function of the artificial liver is relatively simple, mainly purifying, to eliminate the accumulation of toxins in the patient's blood due to the loss or impairment of metabolic function caused by liver function impairment
Due to the single function of the existing artificial liver, it is impossible to deal with the comprehensive situation of patients with severe liver failure, and the patient needs to replace multiple machines, which leads to an increase in the cost of the patient, and also increases the physical burden and psychological pressure of the patient.
Switching between various machines will also increase the learning cost of technicians, increase the difficulty of operation, and increase the demand for storage space

Method used

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  • Combined bioartificial liver supporting system
  • Combined bioartificial liver supporting system
  • Combined bioartificial liver supporting system

Examples

Experimental program
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Embodiment Construction

[0037] Embodiments of the invention are described in detail below, examples of which are illustrated in the accompanying drawings. The embodiments described below by referring to the figures are exemplary only for explaining the present invention and should not be construed as limiting the present invention. In order to demonstrate the practical application of the combined bioartificial liver support system, the following examples will introduce specific components of the support system, so that the application of the support system and the component connection relationship of the support system can be more fully demonstrated And for easy understanding, it should be noted that the protection scope of the present invention is not limited.

[0038] Please refer to figure 1 , figure 1The overall structure of a combined bioartificial liver support system 1 (hereinafter referred to as "support system 1") provided by this embodiment is shown. The support system 1 at least include...

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Abstract

The invention discloses a combined bioartificial liver supporting system. The supporting system at least comprises branch pipelines connected in order, the branch pipelines are a blood input branch pipeline of which an upstream tail end is arranged to be a blood input end, a first slurry separating branch pipeline at least including a first plasma separator, a non- biological cleaning branch pipeline at least including a plasma hemoperfusion apparatus and a bilirubin absorber, a biological cleaning branch pipeline at least including a liver cell culture tank component, a plasma returning branch pipeline of which downstream tail end is arranged to be a blood output end; tee devices are connected among the first plasma separating branch pipeline, the biological cleaning branch pipeline and the non-biological cleaning branch pipeline, between the outlet end of the non-biological cleaning branch pipeline and the biological cleaning branch pipeline, and between an outlet end of the non-biological cleaning branch pipeline and the plasma returning branch pipeline; the tee devices comprise tee joints and branch paths connected with the tee joints; at least two branch paths are provided with current limiting pieces and connection pieces.

Description

technical field [0001] The invention mainly relates to the field of biology and the field of medical equipment, in particular to an artificial liver support system with multiple functions. Background technique [0002] my country is a country with a high incidence of liver disease, and liver disease will eventually develop into liver failure. Due to liver failure, the mortality rate of patients is relatively high, and treatment is also relatively difficult. Clinically, liver transplantation is currently the most effective treatment for liver diseases. Due to the scarcity of donors, high cost and rejection by the human immune system, the application of liver transplantation is limited. At the same time, while waiting for liver transplantation, the patient is still suffering from liver failure, and the patient's physique and physical condition may be affected to the point that he is not suitable for liver transplantation. [0003] At present, the artificial liver will prolong...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/36A61M1/16
CPCA61M1/1698A61M1/3621A61M1/3626A61M1/3653A61M1/3672A61M1/3679A61M1/3689A61M1/369A61M2205/33A61M1/3623A61M1/3482A61M1/3486A61M1/3489A61M1/3493A61M39/22A61M39/28A61M2039/1038C12M21/08C12M23/42C12M29/10A61M1/3496A61M39/105A61M2202/0415A61M2205/3368
Inventor 高毅潘明新冯磊李阳蔡磊何国林翁骏彭青
Owner ZHUJIANG HOSPITAL SOUTHERN MEDICAL UNIV
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