Spray containing melaleuca alternefolia hydrosol and preparation method of spray

A technology of Melaleuca alternifolia and spray, which is applied in the directions of medical preparations containing active ingredients, preparations for skin care, pharmaceutical formulations, etc., can solve the problem of insufficient research on the remaining substances in Melaleuca alternifolia

Inactive Publication Date: 2018-05-04
深圳市润昇源生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] It is generally believed in the prior art that among the oil phase components of the confirmed volatile components of Melaleuca alternifolia, 18 hydrocarbons account for about 30% of the total amount of the oil phase, and alcohols account for about 50%. The study of the remaining substances in Melaleuca melalum is not in-depth

Method used

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  • Spray containing melaleuca alternefolia hydrosol and preparation method of spray
  • Spray containing melaleuca alternefolia hydrosol and preparation method of spray
  • Spray containing melaleuca alternefolia hydrosol and preparation method of spray

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preparation Embodiment 1

[0034] Preparation Example 1: Preparation of Spray

[0035] Dissolve the compound of formula I in water, add other solvents, stabilizers and emulsifiers in sequence, fully shake until clarified, filter, and package. The solvent is selected from one or more of water, glycerin, propylene glycol and ethanol; the stabilizer is selected from one or more of Span, lauryl alcohol and colloidal silicon dioxide; the emulsifier is selected from emulsifiers temperature. Wherein the addition amount of the compound of formula I does not exceed 0.5% of the total amount. Those skilled in the art can understand that any method for preparing sprays in the prior art can prepare the sprays of the present invention, which are all simple improvements to the sprays of the present invention

preparation Embodiment 2

[0036] Preparation Example 2: Preparation of Formula I Compound

[0037] (1) Get 500 grams of leaves of fresh Melaleuca alternifolia, pulverize, put into a distillation tower, heat and pressurize distillation, separate, and recycle extract to obtain pure dew; those skilled in the art can know that the pure dew preparation process is the present Known in the art, those skilled in the art can adopt any other pure dew extraction method, and this all is the simple improvement to the method of the present invention.

[0038] (2) Mix the pure dew in step (1) with ethanol at a mass ratio of 1:8, stir at a constant temperature of about 55°C for 6 hours, and decoct 3 times for 2 hours each time;

[0039] (3) Combine the decoction liquids, filter and concentrate until the relative density at 80° C. is about 1.2, and a pale yellow oily liquid is obtained.

[0040] (4) Use silica gel column chromatography on the light yellow oily liquid, wash with ethanol+water mixed solvent gradient with ...

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PUM

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Abstract

The invention relates to spray containing melaleuca alternefolia hydrosol and a preparation method of the spray. The spray comprises a compound of a formula I extracted from the melaleuca alternefoliahydrosol, as well as available additives for cosmetics. The spray is capable of effectively avoiding ultraviolet injury. The structural formula is as shown in the specification.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular, the invention relates to an extract of Melaleuca alternifolia, a preparation method thereof and the use of the extract as a cosmetic. Background technique [0002] Alternate Melaleuca (Melaleuca ahemifolia) is a woody plant of the Myrtaceae Melaleuca, multi-tree. The colorless to pale yellow light oily liquid obtained by steam distillation of fresh branches and leaves of plants, botanically defined as Melaleuca alternifolia oil, commonly known as "tea tree essential oil". Melaleuca alternifolia has good spectrum bactericidal health care, insect repellent and mosquito repellent effects, and has a pleasant aroma of nutmeg. It is recognized as an excellent natural fragrance, antibacterial agent, and preservative. It is widely used in daily chemical, pharmaceutical, and food industries. Since 1993, my country's Guangdong, Guangxi, Yunnan and other places have successfully introduced Melaleuca...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/49A61K8/9789A61K8/04A61Q17/04A61Q19/08A61Q19/02C07D493/18
CPCA61K8/046A61K8/4973A61K8/97A61K2800/805A61Q17/04A61Q19/02A61Q19/08C07D493/18
Inventor 吴国兴魏泽伟吴伟超
Owner 深圳市润昇源生物科技有限公司
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