Method for preparing skin care compositions applicable to sensitive skin on basis of skin lipidomics

A technology of skin care composition and lipid composition, which is applied in the field of skin care products and preparation of skin care products for people with sensitive skin, can solve the problems of unseen skin care products, achieve the effect of alleviating sensitive skin symptoms, good application prospects, and no skin discomfort

Active Publication Date: 2018-04-13
BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] So far, no lipidomics method has been used to analyze the differences in self-reported sensitive skin surface lipids, let alone skin care products made based on this difference

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1 is applicable to the preparation of the skin care product (cream) of women's sensitive skin

[0036] 1. Select 50 female volunteers with healthy skin, and get 50 female volunteers with self-reported sensitive skin through questionnaire screening. The content of the questionnaire includes the factors that cause sensitivity: physical factors (alternating cold and heat, ultraviolet radiation, wind), chemical factors (skin care products, environmental pollution) and mental factors (stress); degree of sensitivity (including itching, tightness, tingling, burning); the full score is 100 points, and if the score is greater than 70 points, it is considered to belong to the self-reported sensitive skin group. Exclude other skin diseases, systemic diseases, etc.; divide into healthy and sensitive groups;

[0037] 2. After cleaning the face (removing the lipid components secreted by the skin), let the volunteer sit quietly for 30 minutes in a constant temperature and h...

Embodiment 2

[0046] Embodiment 2 is applicable to the preparation of the skin care product (mask) of women's sensitive skin

[0047] 1. Select 50 female volunteers with healthy skin, and get 50 female volunteers with self-reported sensitive skin through questionnaire screening. The content of the questionnaire includes the factors that cause sensitivity: physical factors (alternating cold and heat, ultraviolet radiation, wind), chemical factors (skin care products, environmental pollution) and mental factors (stress); degree of sensitivity (including itching, tightness, tingling, burning); the full score is 100 points, and if the score is greater than 70 points, it is considered to belong to the self-reported sensitive skin group. Exclude other skin diseases, systemic diseases, etc.; divide into healthy and sensitive groups;

[0048] 2. After cleaning the face (removing the lipid components secreted by the skin), let the volunteer sit quietly for 30 minutes in a constant temperature and hu...

Embodiment 3

[0057] Efficacy test and clinical trial of embodiment 3 skin care products of the present invention

[0058] experiment one:

[0059] Select 40 people from the self-reported sensitive skin population in Example 1, use three kinds of test skin care products in stages to carry out the experiment, each stage lasts for 4 weeks, after a stage ends, stop using the test skin care products for 28 days, and carry out the following A staged experiment.

[0060] The three tested skin care products were as follows:

[0061] Tested skin care product 1: face cream prepared according to the method of Example 1

[0062] Tested skin care product 2: prepared according to the method of Example 1, the difference is that no lipid composition is added

[0063] Test skin care product 3: prepared according to the method of Example 1, the difference is that the lipid composition in Example 1 is replaced by the following lipid composition:

[0064] Dimethicone, Stearic Acid, Isononyl Isononanoate, ...

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PUM

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Abstract

The invention discloses a method for preparing skin care compositions applicable to sensitive skin on the basis of skin lipidomics. The method includes analyzing different lipid of skin of sensitive skin population and healthy skin population; adding single components or compound components with appropriate proportions into skin care products according to screened different lipid to obtain the skin care compositions applicable to relieving skin allergy symptoms. The method has the advantages that skin barrier effects can be improved by the skin care compositions prepared by the aid of the method, the skin allergy symptoms can be relieved by the skin care compositions, the skin care compositions are free of skin irritation and can be well received by extensive consumers, and accordingly themethod has an excellent application prospect.

Description

technical field [0001] The invention relates to a method for preparing skin care products, in particular to a method for preparing skin care products suitable for people with sensitive skin based on skin lipidomics. The invention belongs to the technical field of cosmetics. Background technique [0002] The causes of sensitive skin are complex, which can be a comprehensive phenomenon caused by the body's endogenous factors, exogenous factors, etc. alone or in combination. There are many endogenous factors that form sensitive skin, including gender, age, race, genetics, hormone levels, etc. The current main description of the mechanism of sensitive skin is a complex process involving the skin barrier-neurovascular-immune inflammation, in which maintenance of the skin barrier is considered to be a key step in the care of sensitive skin. The influence of lipid content and composition changes on the skin surface can be divided into three aspects: first, changes in skin surface ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/92A61K8/31A61K8/34A61K8/37A61K8/68A61K8/891A61Q19/00
CPCA61K8/31A61K8/345A61K8/37A61K8/375A61K8/68A61K8/891A61K8/922A61K8/925A61K8/927A61Q19/00A61Q19/005
Inventor 何聪芬贾焱江彪崔乐樊琳娜宋丽雅成志伟董坤刘蕾
Owner BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY
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