Three-dimensional porous graphene assembled drug temperature controlled chemotherapy and thermotherapy gastrointestinal tumor device

A three-dimensional porous, graphene technology, applied in the field of tumor treatment, can solve the problems of difficult to completely cure tumors, poor tumor treatment effect, tissue and organ damage, etc.

Pending Publication Date: 2018-03-30
CHINA UNIV OF GEOSCIENCES (WUHAN)
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, there are still some problems in the technical development of hyperthermia, such as: the problem of uneven heat distribution, which will cause the heat in some areas to be insufficient to kill all tumor cells, and the heat in some areas may damage normal cells. It is difficult to cure the tumor completely
There are obviously great defects in the hyperthermia method, that is, the non-specificity of heat transfer, which can easily cause damage to normal tissues and organs around the tumor, and there are also a series of problems such as poor therapeutic effect on deep-seated tumors
[0003] At present, how to effectively overcome the series of defects in tumor treatment technology, such as: how to solve the problem of heat transfer specificity in hyperthermia; how to accurately implement heat targeting and accumulation to tumor sites; how to implement precise temperature control chemotherapy or hyperthermia; How to implement directional and multiple chemotherapy in a targeted manner according to the characteristics of the patient's tumor site; how to organically combine multiple temperature-controlled chemotherapy, hyperthermia and targeted therapy to improve the synergistic effect of tumor treatment, etc. These are series that need to be solved urgently important technical issues

Method used

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  • Three-dimensional porous graphene assembled drug temperature controlled chemotherapy and thermotherapy gastrointestinal tumor device
  • Three-dimensional porous graphene assembled drug temperature controlled chemotherapy and thermotherapy gastrointestinal tumor device

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Embodiment

[0031] Schematic diagram of the structural section of the three-dimensional porous graphene-assembled drug temperature-controlled chemotherapy and hyperthermia device for gastrointestinal tumors of the present invention, as shown in figure 1 Shown; the structural cross-sectional schematic diagram of the three-dimensional porous graphene assembled drug multiple temperature control chemotherapy and hyperthermia tumor apparatus 1 in the device, as figure 2 shown.

[0032] First, two pieces of three-dimensional porous graphene are prepared, and a certain amount of graphene oxide dispersion and graphene nanosheet dispersion are fully mixed, and then transferred to a hydrothermal kettle for hydrothermal reaction. After the hydrothermal reaction is completed, the formed three-dimensional porous graphene columnar body is taken out after the temperature is cooled down. Put the columnar body into the ice room for pre-cooling, and after vacuum freeze-drying, three-dimensional porous gr...

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Abstract

The invention relates to a three-dimensional porous graphene assembled drug temperature controlled chemotherapy and thermotherapy gastrointestinal tumor device, which comprises a three-dimensional porous graphene assembled drug multi-temperature-controlled chemotherapy and thermotherapy tumor instrument, wherein the tumor instrument comprises a three-dimensional porous graphene assembled drug multi-temperature-controlled therapeutic apparatus, a telescopic multi-beam optical fiber rod and a dimming chamber; the three-dimensional porous graphene assembled drug multi-temperature-controlled therapeutic apparatus, the dimming chamber and the telescopic multi-beam optical fiber rod form an integrated controllable telescopic structure together which can generate actions such as linkage extensionand retraction in the whole device; the three-dimensional porous graphene assembled drug multi-temperature-controlled therapeutic apparatus comprises a three-dimensional porous graphene assembled multi-temperature-controlled drug releasing chamber; the three-dimensional porous graphene assembled multi-temperature-controlled drug releasing chamber comprises three-dimensional porous graphene and assembled drugs; and different types of drugs can be released for multiple times under different temperature control conditions. The device in the embodiment of the invention can also be applicable to chemotherapy and thermotherapy for tumors at the throat and tumors in the skin of the human body.

Description

technical field [0001] The invention belongs to the field of tumor treatment, and relates to a multiple temperature-controlled chemotherapy and thermotherapy device, in particular to a three-dimensional porous graphene-assembled drug temperature-controlled chemotherapy and thermotherapy device for gastrointestinal tumors. Background technique [0002] At present, various tumor diseases faced by human beings are increasing year by year, and malignant tumors, namely cancer, have become one of the major diseases that threaten human health globally. At present, the main treatment methods for cancer include chemotherapy, radiotherapy, surgery, etc., but these treatment methods all have certain technical limitations. For example, the drug delivery of chemotherapy has the problem of non-targeting, and the treatment mechanism is single, drug resistance is prone to occur, the side effects are relatively large, and patients should not take it for a long time; and surgical treatment wi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N5/06A61M31/00
CPCA61M31/002A61N5/0603A61N5/0625A61N2005/0609A61N2005/0664A61N2005/0659A61N2005/0653A61M2205/052A61M2205/02A61M2205/3368A61M2205/587A61M2205/583A61M2210/1053A61M2210/005
Inventor 袁曦明袁一楠
Owner CHINA UNIV OF GEOSCIENCES (WUHAN)
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