Antibacterial and dehumidifying dressing and preparation method thereof

Abstract

Belonging to the technical field of medicine, the invention in particular relates to an antibacterial and dehumidifying dressing and a preparation method thereof. The antibacterial and dehumidifying dressing is composed of an adhesive tape layer, an absorbing layer, a dressing layer and a protective film. The dressing layer includes the following components by weight: 2-4 parts of collagen antibacterial peptide, 2-6 parts of jujube pectin, 4-8 parts of chitosan, 2-4 parts of mannose, 1-3 parts of aloe polysaccharide, 3-6 parts of alginate oligosaccharide, 4-8 parts of poly(L-lactic acid), 4-8parts of sodium alginate, 3-6 parts of sodium carboxymethyl cellulose, 1-3 parts of an anti-allergic agent, 1-4 parts of apple polyphenol and 8-12 parts of panthenol. The antibacterial and dehumidifying dressing provided by the invention employs collagen antibacterial peptide, jujube pectin, chitosan and other components for mutual cooperation and coordination, achieves very good inhibitory effecton the growth and reproduction of bacteria, has very good promoting effect on proliferation of fibroblasts, and also has better liquid retention ability and moisture penetrability.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an antibacterial and dehumidifying dressing and a preparation method thereof. Background technique [0002] Traditional wound dressings are divided into dry gauze and oil gauze. Dry traditional dressings can monitor and cover wounds, but cannot be used for infected wounds. The ability to manage exudate is limited. Adhesive wounds will re-damage the new epithelial tissue. The patient needs to change the dressing Pain after. Oily gauze dressings contain petroleum jelly or triglycerides, which can prevent adhesion to the wound, but still cannot promote healing. At the same time, because the liquid secreted by the wound surface cannot penetrate the adhesive plaster layer, it will soak the local skin, make the wound and the surrounding skin white, and in severe cases, the skin will rot, and the wound is difficult to heal. The simple hydrogel type medical dressings conta...

AI Technical Summary

Problems solved by technology

Jujube pectin has the characteristics of low esterification degree and high gel degree, and active factors are bonded to the long chain, in addition to the gelation, stability, and strong water absorption and moisturizing properties of ordinary pectin , it is very effective in promoting wound healing and removing scars, but its antibacterial effect is limited, and it is prone to inflammation such as slight redness, swelling, heat, pain, etc.

[0004] Jujube pectin has the characteristics of low esterification degree and high gelation degree, and active factors are bonded to the long chain. In addition to the gelatinity, stability, and strong water-absorbing and water-retaining properties of ordinary pectin, its The effect of promoting wound healing and removing scars is excellent. Chinese patent application CN103263687A discloses a kind of auxiliary material patch using a mixture of jujube pectin, borneol and alum as a functional auxiliary material layer, which can effectively promote wound healing without adhesion, but its The bactericidal effect is poor, and the wound is prone to redness, swelling and suppuration