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A composition, its preparation method and its application in the field of improving male sexual function

A composition and a technology for sexual function, applied in the field of improving male sexual function, the composition and its preparation field, can solve problems such as health threats, achieve the effects of improving sexual function, increasing serum testosterone content, and increasing the number of captures

Active Publication Date: 2021-03-16
BY HEALTH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In view of this, the present invention provides a composition and its preparation method and its application in the field of improving male sexual function, which solves the technical defect of health care products for improving male sexual function that may pose a potential threat to health in the prior art

Method used

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  • A composition, its preparation method and its application in the field of improving male sexual function
  • A composition, its preparation method and its application in the field of improving male sexual function
  • A composition, its preparation method and its application in the field of improving male sexual function

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] This embodiment is a specific example of the preparation of the product.

[0035] Weigh 20g Epimedium, 20g Morinda officinalis, 10g Psoralen, 2g Lycium barbarum, 15g Rehmannia glutinosa, 1g Cornus officinalis and 14g American ginseng, dissolve in extract solution 1 for extraction, stir and heat at 70°C for 60min, then filter Collect the liquid to obtain the first product 1; wherein, the extract 1 is 65% ethanol. The first product 1 was concentrated at 40°C for 40 minutes to obtain the second product 1. 60 g of the second product 1 was mixed with 10 g of auxiliary material 1, and spray-dried to obtain product 1; wherein, the extract 1 was 65% (v / v) ethanol Solution, excipient 1 is a mixture of maltodextrin and sodium starch glycolate.

[0036] Weigh 15g Epimedium, 15g Morinda officinalis, 2g Psoralen, 20g Lycium barbarum, 20g Rehmannia glutinosa, 10g Cornus officinalis and 1g American ginseng, dissolve in extract solution 2 for extraction, stir and heat at 85°C for 120m...

Embodiment 2

[0043] This example is a specific example of modeling, that is, artificial intervention is used to change normal rats into rats with sexual dysfunction.

[0044] After passing the animal quarantine, 200 male and female SD rats were randomly divided into 10 groups according to body weight, 20 / group, male and female, and the dosage of each group was 0.9g of the product to be tested / rat. Among them, Group 1 to Group 7 were given products 1 to 7 prepared in Example 1, Group 8 was given commercially available drugs for improving male sexual function, Group 9 was a model control group, and Group 10 was a blank control group.

[0045] After the rats were divided into groups, the blank control group underwent sham operation, and the rest of the groups underwent castration. During the operation, rats were anesthetized by intraperitoneal injection of 3% pentobarbital sodium at 1.5 mL / kg body weight, positioned supine, and prepared for skin preparation. A 1 cm long incision was made at t...

Embodiment 3

[0048] This example is a specific example of improving male sexual function by measuring the product prepared in Example 1.

[0049] 3.1 Experimental method

[0050] 3.1.1 General Observations

[0051] During the test period, the survival of the male mice was observed every day, including: diet, activity, hair, skin (ulcer, bleeding) and other conditions once.

[0052] 3.1.2 Mating test

[0053] At night after continuous administration for 30 days, the male mice were placed in the middle box in batches, 1 mouse / box, and after 5 minutes of adaptation to the environment, 1 female mouse was put into each box, and the mating behavior of the animals within 40 minutes was recorded, and then the video was analyzed to observe the following: index:

[0054] Capture latency period: the time from when the female rats were put in to when the male rats caught the female rats for the first time.

[0055] Latency of ejaculation: the time from the injection of female mice to the first eja...

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Abstract

The invention belongs to the field of a health care product, and particularly relates to a composition, a preparation method of the composition and application of the composition to the field of malesexual function improvement. The composition provided by the invention is prepared from the following raw materials of herba epimedii, radix morindae officinalis, fructus psoraleae, fructus lycii, radix rehmanniae preparata, fructus corni and radix panacis quinquefolii. The invention also provides the preparation method of the composition. The invention also provides application of the compositionor a product prepared by the preparation method to the field of male sexual function improvement. Through animal experiment determination, the product prepared by the method can be used for effectively increasing the catching times and the ejaculation times in the mating experiments of single side testicle removal rats and reducing the ejaculation incubation period and catching incubation period;meanwhile, the effects of improving blood serum testosterone content of the single side testicle removal rats, reducing the telotism latent period, improving the sperm motility, increasing the forward linear movement sperm quantity, reducing the nonlinear movement sperm and died sperm quantity and improving the sexual function of the male rats are achieved.

Description

technical field [0001] The invention belongs to the field of health care products, and in particular relates to a composition, a preparation method thereof and an application in the field of improving male sexual function. Background technique [0002] Sexual function is the instinct of human beings to carry out activities, and it is the basis of fertility and reproduction. Male sexual function is the guarantee for men to carry out sexual activities. The disorder of male sexual function is a disease. Specifically, male sexual dysfunction refers to the five stages of male sexual activity such as sexual desire, penile erection, sexual intercourse, orgasm, and ejaculation, among which, abnormalities in a certain stage or several stages or the entire stage affect sexual function. The activity is proceeding normally. [0003] In the prior art, most of the health products sold in the conventional market claiming to relieve physical fatigue and improve male sexual function achieve...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/815A61P15/00A61P15/08A23L33/105
CPCA23V2002/00A61K36/258A61K36/296A61K36/40A61K36/487A61K36/746A61K36/804A61K36/815A23L33/105A61K2300/00A23V2200/30A23V2250/21
Inventor 李开莹胡芳黄远英殷光玲张旭光
Owner BY HEALTH CO LTD
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