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A lung cancer screening kit

A reagent and lung cancer technology, applied in the field of lung cancer screening kits, can solve problems such as reports of no SOST expression, and achieve good clinical application prospects

Active Publication Date: 2019-09-06
成都医学院第一附属医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, there is no report on the expression of SOST in lung cancer

Method used

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  • A lung cancer screening kit
  • A lung cancer screening kit

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Experimental program
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Embodiment 1

[0024] Example 1 Detection of the expression level of SOST in lung cancer

[0025] 1. Experimental materials

[0026] Lung cancer tissue microarrays (HLugS060CD01 and HLug-Ade050CD-01) were purchased from Shanghai Xinchao Biology. The microarray contains histopathological sections of lung cancer, in which:

[0027] HLugS060CD01 tissue chip is lung squamous cell carcinoma disease course chip: including 5 cases of normal human lungs, 22 cases of paracancerous and primary lung squamous cell carcinoma (clinical stage 1, 2, 3, 4) and 3 metastatic lung squamous cell carcinoma 4 cases and 4 cases of negative and positive lymph nodes of lung squamous cell carcinoma.

[0028] HLug-Ade050CD-01 tissue chip is a lung adenocarcinoma disease course chip: including 5 cases of normal human lung, 14 cases of paracancerous / primary lung adenocarcinoma (clinical stage 1, 2, 3, 4) each, lung adenocarcinoma There were 4 cases of cancer metastasis, 7 cases of negative lymph nodes and 6 cases of p...

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Abstract

The invention discloses a kit for screening lung cancer. The kit comprises an optional kit for detecting the expression level of an SOST protein. The invention further discloses use of the kit for detecting the expression level of the SOST protein in the preparation of a kit for screening the lung cancer. By detecting the expression level of the SOST protein, the risk of a to-be-inspected person suffering from the lung cancer can be judged, and the kit can be applied to the clinical auxiliary diagnosis of the lung cancer, so that effective basis is provided for the utilization of relevant treatment measures or decisions by patients, and the kit has good clinical application prospects.

Description

technical field [0001] The invention relates to a lung cancer screening kit. Background technique [0002] Among the morbidity and mortality of malignant tumors, lung cancer accounts for 13.0% and 19.4% respectively, ranking first among malignant tumors. Moreover, due to factors such as the intensification of China's aging population and the rejuvenation of the smoking population, the population base of lung cancer patients is still on the rise. Due to the heterogeneity of lung cancer, the treatment effect of the same treatment method on lung cancer is often different. Therefore, in the clinical research and clinical treatment of lung cancer, an important part is to classify and stage lung cancer to minimize its heterogeneity. Improve treatment efficiency. [0003] At present, according to the degree of differentiation and morphological characteristics of various types of lung cancer, lung cancer can be divided into small cell lung cancer, adenocarcinoma, and squamous cell...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/68G01N33/574
Inventor 许颖吴东明张涛杨菁
Owner 成都医学院第一附属医院
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