A kind of method that prepares polypolic acid C from poria cocos
A technology of porcine acid and polyporus, applied in the directions of steroids, organic chemistry, etc., can solve the problems of inability to meet large-scale preparation, generally low yield, weak targeting, etc., and achieves low cost, high purity, and low cost of chromatography solvent. The effect of low environmental pollution
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0034] A method for preparing polyporic acid C from Poria cocos, specifically comprising the following steps:
[0035] (1) Poria cocos piece 120kg is crushed into powder, adds the 85% ethanol of Poria cocos powder 15 times weight volume (being that the weight volume ratio of Poria cocos powder and 85% ethanol is 1kg:15L), reflux extraction 3 times, each 1 hour, get the extract;
[0036] (2) Combine the extracts, filter, and concentrate the obtained filtrate under reduced pressure to obtain a concentrated solution with a specific gravity of 1.2 at 60° C.;
[0037] (3) The concentrated solution was extracted 3 times with equal volumes of ethyl acetate, and the ethyl acetate extraction layer was concentrated under reduced pressure to obtain a thick extract of the ethyl acetate part;
[0038] (4) Add 1.5-2 times the weight of 60-80 mesh silica gel to the thick extract of the ethyl acetate part to mix the sample to obtain the sample silica gel A;
[0039] (5) sample silica gel A ...
Embodiment 2
[0047] A method for preparing polyporic acid C from Poria cocos, specifically comprising the following steps:
[0048] (1) 150 kg of Poria cocos block is crushed into powder, and 70% ethanol of 20 times the weight volume of Poria cocos powder is added, and reflux extraction is performed 4 times, each time for 2 hours, to obtain an extract;
[0049] (2) Combine the extracts, filter, and concentrate the obtained filtrate under reduced pressure to a concentrated solution with a specific gravity of 1.1 at 60°C;
[0050] (3) The concentrated solution is extracted 4 times with equal volumes of ethyl acetate, and the ethyl acetate extraction layer is concentrated under reduced pressure to obtain a thick extract of the ethyl acetate part;
[0051] (4) Add 1.5-2 times 60-80 mesh silica gel to the thick extract of the ethyl acetate part and mix the sample to obtain the sample silica gel A;
[0052] (5) sample silica gel A adopts vacuum liquid chromatography to carry out rough separatio...
Embodiment 3
[0060] A method for preparing polyporic acid C from Poria cocos, specifically comprising the following steps:
[0061] (1) 200 kg of Poria cocos block is crushed into powder, and 95% ethanol of 10 times the weight volume of Poria cocos powder is added, and reflux extraction is performed 5 times, each time for 3 hours, to obtain an extract;
[0062] (2) Combine the extracts, filter, and concentrate the obtained filtrate under reduced pressure to a concentrated solution with a specific gravity of 1.3 at 60°C;
[0063] (3) The concentrated solution is extracted 5 times with equal volumes of ethyl acetate, and the ethyl acetate extraction layer is concentrated under reduced pressure to obtain a thick extract of the ethyl acetate part;
[0064] (4) Add 1.5-2 times 60-80 mesh silica gel to the thick extract of the ethyl acetate part and mix the sample to obtain the sample silica gel A;
[0065] (5) sample silica gel A adopts vacuum liquid chromatography to carry out rough separatio...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com