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Biotin hair loss preventing nutrient solution

A biotin, nutrient solution technology, applied in drug combinations, cosmetics, skin diseases, etc., can solve problems such as hair loss that cannot be fundamentally solved, and achieve the effects of improving hair follicle microcirculation, improving hair follicle atrophy, and stimulating cell metabolism.

Inactive Publication Date: 2017-10-31
三九军大药业(厦门)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] But anti-hair loss shampoo is just a hair care product, at best it can only play an auxiliary role, but it can never fundamentally solve the problem of hair loss

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Active ingredient weight ratio:

[0031] D panthenol 0.5%; aloe vera extract 3%; hair growth hormone solution 5%.

[0032] The preparation method of the hair growth hormone solution is as follows: first, fully disperse biotinyl tripeptide-1, oleanolic acid and apigenin with CO40, then add water to dissolve, add 1,3-butanediol and stir to form a uniform A solution of 250 ppm biotinyl tripeptide-1, 300 ppm oleanolic acid and 500 ppm apigenin. The volume ratio of water and 1,3-butanediol in the solution is 2:8.

[0033] The weight ratio of matrix components: IPIS oil 0.5%; camellia oil 1%; cetearyl alcohol; disodium EDTA 0.1%; citric acid 0.2%; glycerin 1%; Aminomethylsiloxane 0.5%; Preservative (composed of Benzyl Alcohol, Methylchloroisothiazolinone, and Methylisothiazolinone) 0.1%; Dipalmitoyloxyethyldimethylammonium Chloride 1%; Hydroxyethylcellulose 0.5%. The balance is deionized water.

[0034] Preparation method: heat the water-phase raw materials to 80-85°C, h...

Embodiment 2

[0036] Active ingredient weight ratio:

[0037] D panthenol 0.1%; aloe extract 1%; hair growth hormone solution 3%.

[0038] The preparation method of the hair growth hormone solution is as follows: first, fully disperse biotinyl tripeptide-1, oleanolic acid and apigenin with CO40, then add water to dissolve, add 1,3-butanediol and stir to form a uniform A solution of 250 ppm biotinyl tripeptide-1, 300 ppm oleanolic acid and 500 ppm apigenin. The volume ratio of water and 1,3-butanediol in the solution is 2:8.

[0039] Weight ratio of matrix components: IPIS oil 2%; tea oil 3%; cetearyl alcohol; disodium EDTA 0.5%; citric acid 1%; glycerin 5%; Aminomethylsiloxane 1%; Preservative (composed of Benzyl Alcohol, Methylchloroisothiazolinone, and Methylisothiazolinone) 0.3%; Dipalmitoyloxyethyldimethylammonium Chloride 3%; Hydroxyethylcellulose 1%. The balance is deionized water.

[0040] Preparation method: heat the water-phase raw materials to 80-85°C, homogenize for 3-5 minu...

Embodiment 4

[0047]Example 4 [This example is a supplementary example to prove the effect of this experiment, please confirm whether the following data is feasible? If other data are available, other experimental data can also be supplemented to verify the effect.

[0048] Select 2,000 hair loss patients between 30 and 40 years old in Guangdong Province; divide them into two groups, each group randomly selects 1,000 people, the first group tries this product (the product prepared in Example 1), and the second group is positive The control group used minoxidil. The method of use is to smear the drug to be tested three times on the scalp every day, and the effects are shown in Table 1:

[0049] Table 1. Product Effect Test Data Sheet

[0050] Effective (number of people) Effective rate (%)

[0051] After 30 days (first group) 468 46.8

[0052] After 30 days (second group) 244 24.4

[0053] After 60 days (first group) 609 60.9

[0054] After 60 days (second group) 349 34.9

[0055] Aft...

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PUM

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Abstract

The invention relates to the technical field of cosmetics, and in particular discloses a biotin hair loss preventing nutrient solution. The nutrient solution consists of the following active ingredients in percentage by weight: 0.1-1% of D-panthenol, 1-5% of an aloe extract and 3-10% of a hair growth promoting hormone solution. The hair growth promoting hormone solution can effectively prevent and treat alopecia caused by such reasons as (1) insufficient blood circulation and poor scalp micro-circulation, (2) hair follicle atrophy which is caused when testosterone is transformed into male sex hormone, namely dihydrotestosterone (DHT), by virtue of 5[alpha]-reductase, (3) hair can't be fixed into dermal papillae due to aging of hair follicles and the like; therefore, purposes of resisting aging of the hair follicles and preventing hair loss can be achieved.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a biotin anti-hair loss nutrient solution. Background technique [0002] The essential ingredients for hair growth are the result of the physical interaction between the skin epidermis and the dermis, where keratinocytes and fibroblasts are compressed in the dermis. Moreover, the collagen and mucopolysaccharides rich in dermal hair milk are in close contact with the keratinocyte and fibroblast populations, promoting the necessary chemical reactions for the generation of the hair shaft. The importance of collagen IV and laminin should be emphasized, since these matrices make up the matrix membrane (hyaline membrane) at the epidermal-dermal junction and most of the dermal hair milk, which can be seen as the hair growth Substrate engine. [0003] Alopecia is the phenomenon of hair falling out. The hair that falls off normally is the hair that is in the catagen and telogen phase...

Claims

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Application Information

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IPC IPC(8): A61K8/9794A61K8/42A61K8/64A61K8/49A61K8/63A61Q5/12A61P17/14
CPCA61K8/42A61K8/498A61K8/63A61K8/64A61K8/97A61Q5/12
Inventor 黄志强
Owner 三九军大药业(厦门)有限公司
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