Nebulizer for nasal fluid formulations

Abstract

A nebulizer (100) for a nasal fluid formulation having a reservoir (10) containing at least one dose of a fluid formulation, a dispensing system (20) for dispensing a fluid each time the nebulizer is activated The dosage (D) of the preparation is atomized through the atomizing hole (35) to produce a spray axially extending from the atomizing hole (35), and the atomizer (100) has a function simultaneously with the dispensing system (20). Activated secondary flow generation system (40), said secondary flow generation system (40) has a secondary flow guide (41) provided with a discharge hole (45), said discharge hole (45) along the spray The axial direction of the atomization hole (35) is arranged downstream of the atomization hole (35), and the secondary flow extends from the discharge hole (45) along an axis (B) relative to the axis (A) of the spray An angle (α) is formed and intersects the axis (A) of the spray, thereby deforming and / or deflecting the spray.

Description

technical field [0001] The present invention relates to a nebulizer for nasal fluid formulations, especially liquid formulations. Background technique [0002] The nasal cavity is divided longitudinally on both sides by the septum. Each nasal cavity is composed first of the nose and then of the nasal flaps. The nasal flap has a special geometry. It extends over a depth of about 1 cm, has a vertical profile of about 3 to 4 cm and a width of about 1 to 3 mm. After passage of the nasal valve, the nasal cavity has a larger chamber (approximately 7 cm high and 2 to 3 cm wide). The turbinates face the nasal flap. Above the turbinates is the roof of the nasal cavity, with the ethmoid bones, olfactory bulb, and olfactory nerve. image 3 is an image of a nasal anatomical model showing nose 1 , nasal flap 2 , turbinate 3 and ethmoid 4 . [0003] Nasal liquid medicament nebulizers are well known in the art. These nebulizers produce a straight spray in a solid angle, as shown in F...

AI Technical Summary

Problems solved by technology

[0005] These prior art nebulizers are complex to implement and in particular represent considerable modification to standard nasal nebulizers

Also, with fine particles, there is the question of overall efficiency of deposition in the nasal cavity

Indeed, a portion of the fine particles generally does not reach the entire nasal cavity (see especially Moller W, Saba GK, Haussinger K, Becker S, Keller M, Schuschnig U, Rhinology publication "Nasal Inhalation of Pulsating Aerosol: Lung, Sinus, and Nasal Deposition ", 2011 Aug; 49(3):286-91), therefore, the nebulizer is inefficient and the treatment is inefficient

Images