Composition and cosmetics having acne-removing effect
A technology of composition and cosmetics, which is applied in the direction of cosmetics, medical preparations containing active ingredients, cosmetic preparations, etc., can solve the problems of repeated occurrence, unsatisfactory effect, and occasional acne, so as to achieve the purpose of inhibiting secretion, good Broad-spectrum antibacterial ability, effect of reducing excessive secretion
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Embodiment 1
[0029] Example 1 Preparation of Drosera rotundum Extract, Sappanwood Extract, Willow Orchid Extract, and Orris Root Extract
[0030] The extract of sundew with round leaves is extracted according to the following method: the extract of sundew with round leaves is extracted according to the following method: take the whole herb of sundew with round leaves, dry and pulverize it through a 60-mesh sieve, Take 100g each time and add to CO 2 In the supercritical extractor, select ethanol as the entrainer, the volume percentage of the entrainer in the total extraction solvent is 2%, the extraction pressure is 30Mpa, the temperature is 40°C, the extraction time is 2h, and the flow rate of the extractant is 30L / h. Distilled water (an appropriate amount of propylene glycol can be added to aid dissolution) was adjusted to 1000mL, and then filtered with a 0.45μm filter membrane to obtain the sundew extract with a concentration of 0.1g / mL.
[0031] The sumac extract is extracted according...
Embodiment 2
[0034] Example 2 Inhibition of 5а-reductase experiment
[0035] 1. Experimental principle
[0036] Acne is a disease caused by multiple factors, and local abnormality of androgen metabolism is one of the most important causes.
[0037] Excessive sebum can lead to increased volume of sebaceous glands and increased sebum secretion, abnormal keratinization of the pilosebaceous gland ducts, resulting in poor sebum excretion, the formation of fat plugs, and acne. In sebocytes, androgen can be converted into more active dihydrotestosterone (DHT) under the action of 5а-reductase, which further stimulates sebum secretion, thereby enhancing the ability to induce acne. Therefore, inhibiting 5а-reductase can reduce the secretion of sebum and achieve the effect of inhibiting acne.
[0038] 5а-reductase catalyzes the conversion of testosterone into dihydrotestosterone with the participation of reduced coenzyme II. If there is a 5а-reductase inhibitor, this reaction process can be inhibit...
Embodiment 3
[0061] Example 3 Preparation of Composition with Acne Removing Efficacy
[0062] Get sundew extract 60g, Sappan extract 40g, willow orchid extract prepared according to the method of Example 1
[0063] 40 g of the extract and 10 g of the orris root extract were mixed uniformly to obtain the composition with anti-acne effect of Example 3.
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