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Isolated organ storage system

An isolated organ, preservation system technology, applied in the field of medical equipment, can solve the problems of secondary infection organ function, failure, preservation failure, etc.

Pending Publication Date: 2017-09-15
SHANGHAI YANGPU SHIDONG HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the process of in vivo preservation, severe secondary infection or failure of a certain organ often occurs, resulting in the failure of the overall preservation, which in turn leads to the waste of donor organs and failure of transplantation
In vivo preservation is expensive and risky

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0097] Such as Figure 1 ~ Figure 4 An isolated organ preservation system is shown, including a donor's own blood collection device, a mutual pull reverse-phase pulsating pump 2, a first roller single pump 3, an oxygenator 4, an isolated organ heat preservation device, and a blood warming device 5. Oxygen supply device 6, filter 7, waste liquid bag 8, urine collection device and bile collection device, in which:

[0098] The isolated organ heat preservation and blood warming device 5 includes a transparent heat preservation cover 51, a medical silicone membrane 53 and a box body 54, wherein:

[0099]A number of openings 511 are provided on the transparent heat preservation cover 51, and a leak-proof snap-type rubber seal ring 52 is installed on the edge of the transparent heat-preservation cover 51, and the medical silicone film 53 is arranged on the edge of the leak-proof snap-type rubber seal ring 52. On the inner side, a circle of grooves for clamping on the edge of the bo...

Embodiment approach

[0111] A method for implementing combined preservation of an isolated liver and kidney using the above-mentioned isolated organ preservation system, comprising the following steps:

[0112] Step a. The system output end of the isolated organ preservation system is short-circuited to the input end, and the Luer connector connected to the blood pool 1 is opened for exhaust;

[0113] Step b. Preflushing: Inject 1000ml of normal saline + 2ml of heparin into the blood pool 1, open the Luer connector and the first injection port that communicate with the blood pool 1, and start the mutual-pulling reversed-phase pulsation pump 2 and the first roller Single pump 3, self-circulation for 30 minutes, fully heparinized, and the gas in the pipeline is discharged, and the isolated organ heat preservation and blood warming device 5 are started to reach the set temperature;

[0114] Step c1. Collect all the blood of the donor, and inject 2000ml of blood into the blood pool through the first l...

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Abstract

The invention relates to the technical field of medical equipment, and in particular relates to an isolated organ storage system, which comprises a donor blood collection device, a complementary-pull type antiphase beating pump, a first roller single pump, an oxygenator, an isolated organ thermal insulation device, a blood heating device, an oxygen supply device, a filter, a waste liquid bag, an urine collection device, and a bile collection device. The isolated organ storage system of the invention is based on a novel blood pump (i.e. complementary-pull type antiphase beating pump), and integrates the membrane type oxygenator, the filter, the roller single pump and necessary monitoring sensors. The invention provides a pseudo-ecological isolated organ storage method and storage system. To this end, the invention in particular provides the corresponding isolated organ obtaining method and the thermal insulation and heating device. The invention aims to maximally prolong the storage time of isolated organs (liver, kidney) to facilitate the transportation and repair, thereby improving transplantation success rate and receptor survival rate.

Description

technical field [0001] The invention relates to the technical field of medical equipment, in particular to an isolated organ preservation system. Background technique [0002] Organ transplantation is a major advance in human medical science in the 20th century, bringing hope to the treatment of various end-stage organ diseases. At present, more than 700,000 cases (times) of various organ transplants have been performed in the world. With the development of surgical techniques and the emergence of new immunosuppressants, the survival rate of organ transplantation has been greatly improved, and the number of patients waiting for transplantation is increasing year by year. In order to alleviate the contradiction of organ shortage, cardiac death donors (DCD) have gradually become an Therefore, higher requirements are put forward for organ preservation technology in clinical practice. Organ preservation techniques mainly include static cryopreservation (SCS) and mechanical per...

Claims

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Application Information

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IPC IPC(8): A01N1/02A61B17/12
CPCA01N1/0242A01N1/0247A61B17/12A61B2017/12004
Inventor 方旭晨高晓刚余均平张舟
Owner SHANGHAI YANGPU SHIDONG HOSPITAL
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